Wang Zhengxi, Dong Fang, Sun Yaning, Wang Juan, Zhang Ming, Xue Ting, Ren Yan, Lv Xiaoqi, Yuan Kai, Yu Dahua
Inner Mongolia Key Laboratory of Pattern Recognition and Intelligent Image Processing, School of Information Engineering, Inner Mongolia University of Science and Technology, Baotou, China.
College of Information Engineering, Inner Mongolia University of Technology, Hohhot, China.
Front Neurosci. 2022 Nov 9;16:1026835. doi: 10.3389/fnins.2022.1026835. eCollection 2022.
Exposure to nicotine is the first cause of entirely preventable death killing, which is commonly initiated in adolescence. Previous studies revealed the changes of electroencephalography (EEG) and inhibition control in smokers. However, little is known about the specific link between alpha coherence during the resting state and inhibition control ability in young smokers. The present study aimed to investigate inter-hemispherical and frontal-parietal alpha coherence changes and assessed the relationships between alpha coherence and inhibition control in young smokers. We collected resting-state EEG data from 23 young smokers and 24 healthy controls. Inhibition control ability was assessed by a Go/NoGo task. Compared to healthy controls, young smokers exhibited increased inter-hemispherical and frontal-parietal alpha coherence. Furthermore, young smokers committed more NoGo errors in the Go/NogGo task. It is noteworthy that alpha coherence at the frontal electrode sites was positively correlated with NoGo errors in healthy controls, whereas inverse correlations were observed in young smokers. Our findings suggested that alterations of alpha coherence may provide support to the earlier nicotine-dependence-related research findings, which may help us to understand the neuropathology of inhibitory control in young smokers.
接触尼古丁是完全可预防死亡的首要原因，这种情况通常始于青少年时期。先前的研究揭示了吸烟者脑电图（EEG）的变化以及抑制控制能力的变化。然而，对于年轻吸烟者静息状态下的α波相干性与抑制控制能力之间的具体联系，人们知之甚少。本研究旨在调查年轻吸烟者半球间和额顶叶α波相干性的变化，并评估α波相干性与抑制控制能力之间的关系。我们收集了23名年轻吸烟者和24名健康对照者的静息状态EEG数据。通过Go/NoGo任务评估抑制控制能力。与健康对照者相比，年轻吸烟者的半球间和额顶叶α波相干性增加。此外，年轻吸烟者在Go/NoGo任务中出现更多的NoGo错误。值得注意的是，在健康对照者中，额叶电极部位的α波相干性与NoGo错误呈正相关，而在年轻吸烟者中则观察到负相关。我们的研究结果表明，α波相干性的改变可能为早期与尼古丁依赖相关的研究结果提供支持，这可能有助于我们理解年轻吸烟者抑制控制的神经病理学。
