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[骨质疏松症:诊断与治疗]

[Osteoporosis: diagnostics and treatment].

作者信息

Stumpf Ulla, Kraus Moritz, Ladurner Roland, Neuerburg Carl, Böcker Wolfgang

机构信息

Klinik für Orthopädie und Unfallchirurgie, Muskuloskelettales Universitätszentrum München (MUM), Klinikum der Universität München, LMU München, Marchioninistr. 15, 81377, München, Deutschland.

Klinik für Allgemein-, Viszeral- und Thoraxchirurgie, Martha-Maria Krankenhaus, München, Deutschland.

出版信息

Z Gerontol Geriatr. 2022 Dec;55(8):703-714. doi: 10.1007/s00391-022-02148-x.

DOI:10.1007/s00391-022-02148-x
PMID:36445487
Abstract

Osteoporosis is the most common systemic skeletal disease worldwide. Its consequences have a substantial impact on the quality of life of patients and increases the overall morbidity and mortality. Standardized diagnostic procedures and treatment recommendations have been available for years as German and international (S3) guidelines. Nevertheless, there is a considerable gap in the diagnosis and adequate treatment of osteoporosis, especially in Germany. The aim is to detect the disease at an early stage and to establish a specific and consistent treatment of osteoporosis. In this way the quality of life and independence of those affected can be maintained over a long period. In the acute and permanent treatment of manifest osteoporosis, surgeons, orthopedic and trauma surgeons play a key role.

摘要

骨质疏松症是全球最常见的全身性骨骼疾病。其后果对患者的生活质量有重大影响,并增加了总体发病率和死亡率。作为德国和国际(S3)指南,标准化的诊断程序和治疗建议已经存在多年。然而,在骨质疏松症的诊断和充分治疗方面仍存在相当大的差距,尤其是在德国。目标是在疾病早期进行检测,并建立针对骨质疏松症的特定且一致的治疗方法。通过这种方式,可以长期维持患者的生活质量和独立性。在明显骨质疏松症的急性和长期治疗中,外科医生、骨科和创伤外科医生起着关键作用。

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[Osteoporosis: diagnostics and treatment].[骨质疏松症:诊断与治疗]
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本文引用的文献

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Reduced Awareness for Osteoporosis in Distal Radius Fracture Patients Compared to Patients with Proximal Femur Fractures.与股骨近端骨折患者相比,桡骨远端骨折患者对骨质疏松症的认知度较低。
J Clin Med. 2021 Feb 19;10(4):848. doi: 10.3390/jcm10040848.
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The Short Physical Performance Battery (SPPB): A Quick and Useful Tool for Fall Risk Stratification Among Older Primary Care Patients.简易体能测试组合(SPPB):老年初级保健患者跌倒风险分层的快速有效工具。
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2020 recommendations for osteoporosis treatment according to fracture risk from the Swiss Association against Osteoporosis (SVGO).
2020 年瑞士骨质疏松症防治协会(SVGO)基于骨折风险的骨质疏松治疗建议。
Swiss Med Wkly. 2020 Sep 29;150:w20352. doi: 10.4414/smw.2020.20352. eCollection 2020 Sep 21.
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A decade of FRAX: how has it changed the management of osteoporosis?十年 FRAX:它如何改变了骨质疏松症的管理?
Aging Clin Exp Res. 2020 Feb;32(2):187-196. doi: 10.1007/s40520-019-01432-y. Epub 2020 Feb 11.
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One Year of Romosozumab Followed by Two Years of Denosumab Maintains Fracture Risk Reductions: Results of the FRAME Extension Study.罗莫佐单抗治疗 1 年后序贯地舒单抗治疗 2 年可维持骨折风险降低:FRAME 扩展研究结果。
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Antiresorptive therapy and risk of mortality and refracture in osteoporosis-related hip fracture: a nationwide study.抗吸收治疗与骨质疏松相关髋部骨折的死亡率及再骨折风险:一项全国性研究
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Unfallchirurg. 2015 Nov;118(11):904. doi: 10.1007/s00113-015-0076-x.