Faculty of Medicine, University of British Columbia, Vancouver, BC, V6T 1Z3, Canada.
Department of Anesthesia and Pain Medicine, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, M5T 2S8, Canada.
BMC Anesthesiol. 2022 Nov 30;22(1):366. doi: 10.1186/s12871-022-01912-1.
Obstructive sleep apnea (OSA) is a common disorder that is highly associated with postoperative complications. The STOP-Bang questionnaire is a simple screening tool for OSA. The objective of this systematic review and meta-analysis is to evaluate the validity of the STOP-Bang questionnaire for screening OSA in the surgical population cohort.
A systematic search of the following databases was performed from 2008 to May 2021: MEDLINE, Medline-in-process, Embase, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, PsycINFO, Journals @ Ovid, Web of Science, Scopus, and CINAHL. Continued literature surveillance was performed through October 2021.
The systematic search identified 4641 articles, from which 10 studies with 3247 surgical participants were included in the final analysis. The mean age was 57.3 ± 15.2 years, and the mean BMI was 32.5 ± 10.1 kg/m with 47.4% male. The prevalence of all, moderate-to-severe, and severe OSA were 65.2, 37.7, and 17.0%, respectively. The pooled sensitivity of the STOP-Bang questionnaire for all, moderate-to-severe, and severe OSA was 85, 88, and 90%, and the pooled specificities were 47, 29, and 27%, respectively. The area under the curve for all, moderate-to-severe, and severe OSA was 0.84, 0.67, and 0.63.
In the preoperative setting, the STOP-Bang questionnaire is a valid screening tool to detect OSA in patients undergoing surgery, with a high sensitivity and a high discriminative power to reasonably exclude severe OSA with a negative predictive value of 93.2%.
PROSPERO registration CRD42021260451 .
阻塞性睡眠呼吸暂停（OSA）是一种常见疾病，与术后并发症高度相关。STOP-Bang 问卷是一种用于 OSA 的简单筛查工具。本系统评价和荟萃分析的目的是评估 STOP-Bang 问卷在手术人群中筛查 OSA 的有效性。
从 2008 年至 2021 年 5 月，我们对以下数据库进行了系统搜索：MEDLINE、正在处理的 Medline、Embase、Cochrane 对照试验中心注册库、Cochrane 系统评价数据库、PsycINFO、Ovid 期刊、Web of Science、Scopus 和 CINAHL。2021 年 10 月继续进行文献监测。
系统搜索共确定了 4641 篇文章，其中 10 项研究共纳入 3247 名手术参与者，最终纳入分析。平均年龄为 57.3±15.2 岁，平均 BMI 为 32.5±10.1kg/m，男性占 47.4%。所有、中重度和重度 OSA 的患病率分别为 65.2%、37.7%和 17.0%。STOP-Bang 问卷对所有、中重度和重度 OSA 的汇总敏感性分别为 85%、88%和 90%，特异性分别为 47%、29%和 27%。所有、中重度和重度 OSA 的曲线下面积分别为 0.84、0.67 和 0.63。
在术前情况下，STOP-Bang 问卷是一种有效的筛查工具，可用于检测接受手术的患者的 OSA，其敏感性高，具有较高的鉴别能力，可以合理排除中重度 OSA 的可能性，阴性预测值为 93.2%。
PROSPERO 注册 CRD42021260451。
