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鼻窦区域转移瘤提示隐匿性原发灶:2例病例系列报道并文献复习

Metastasis in Sinonasal Region Revealing a Silent Primary: A Series of 2 Cases with Review of Literature.

作者信息

Priya Madhu, Xavier Joyson, John Saumya, Angral Sumeet, Malhotra Manu, Bhardwaj Abhishek, Varshney Saurabh, Venkatesan Sneha

机构信息

Department of Otorhinolaryngology & Head-Neck Surgery, All India Institute of Medical Sciences, Rishikesh, Uttarakhand 249203 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):1967-1972. doi: 10.1007/s12070-020-01931-9. Epub 2020 Jul 4.

DOI:10.1007/s12070-020-01931-9
PMID:36452680
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9702466/
Abstract

Metastasis to the nasal cavity and paranasal sinuses are very rare and only few cases have been reported so far. Metastatic nasal mass with silent primary renal cell carcinoma (RCC) is even rarer. So are giant cell tumors which rarely affects soft tissues whether superficial or deep. These rarely occur in nasal cavity. We would like to discuss 2 cases-one being a 74 year old female with a solitary asymptomatic extensive metastatic lesion in sinonasal area of silent primary renal cell carcinoma and other being a 38 year old female multiple lytic expansile lesions in facial and skull bones who was previously treated for giant cell tumor of long bone-tibia. We aim to bring their occurrence to notice as they are rare, to highlight importance of these tumors in differential diagnosis of sinonasal masses and treatment options for the same.

摘要

转移至鼻腔和鼻窦非常罕见,迄今为止仅有少数病例报道。伴有隐匿性原发性肾细胞癌(RCC)的转移性鼻腔肿物更为罕见。巨细胞瘤同样罕见,它很少累及浅表或深部软组织,在鼻腔更是罕见。我们想讨论2例病例——1例是一名74岁女性,有无症状的孤立性广泛转移病灶位于隐匿性原发性肾细胞癌的鼻窦区域;另1例是一名38岁女性,面部和颅骨有多个溶骨性膨胀性病灶,她曾接受过长骨(胫骨)巨细胞瘤的治疗。我们旨在引起大家对这些罕见病例的关注,强调这些肿瘤在鼻腔肿物鉴别诊断中的重要性以及相应的治疗选择。

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Metastasis in Sinonasal Region Revealing a Silent Primary: A Series of 2 Cases with Review of Literature.鼻窦区域转移瘤提示隐匿性原发灶:2例病例系列报道并文献复习
Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):1967-1972. doi: 10.1007/s12070-020-01931-9. Epub 2020 Jul 4.
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本文引用的文献

1
Giant Cell Tumor of Bone - An Overview.骨巨细胞瘤——概述
Arch Bone Jt Surg. 2016 Jan;4(1):2-9.
2
RENAL CELL CARCINOMA METASTASIS TO THE SINONASAL CAVITY: CASE REPORT.肾细胞癌转移至鼻窦腔:病例报告
Acta Clin Croat. 2015 Jun;54(2):223-6.
3
Risk factors for pulmonary metastases from giant cell tumor of bone.骨巨细胞瘤肺转移的危险因素。
J Bone Joint Surg Am. 2015 Mar 4;97(5):420-8. doi: 10.2106/JBJS.N.00678.
4
Giant cell tumor: rapid recurrence after cessation of long-term denosumab therapy.骨巨细胞瘤:长期地诺单抗治疗停止后快速复发。
Skeletal Radiol. 2015 Jul;44(7):1027-31. doi: 10.1007/s00256-015-2117-5. Epub 2015 Feb 26.
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Giant cell tumour of bone: new treatments in development.骨巨细胞瘤:正在研发的新疗法
Clin Transl Oncol. 2015 Jun;17(6):419-30. doi: 10.1007/s12094-014-1268-5. Epub 2015 Jan 24.
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Giant cell tumor of bone.骨巨细胞瘤
Oncologist. 2014 Nov;19(11):1207. doi: 10.1634/theoncologist.2014-0267.
7
Giant cell tumor of bone: review, mimics, and new developments in treatment.骨巨细胞瘤:综述、模拟及治疗的新进展。
Radiographics. 2013 Jan-Feb;33(1):197-211. doi: 10.1148/rg.331125089.
8
Renal cell carcinoma metastasis to the paranasal sinuses and orbit.肾细胞癌转移至鼻窦和眼眶。
BMJ Case Rep. 2012 Mar 27;2012:bcr0120125492. doi: 10.1136/bcr.01.2012.5492.
9
Targeted therapy for advanced renal cell cancer (RCC): a Cochrane systematic review of published randomised trials.晚期肾细胞癌(RCC)的靶向治疗:一项对已发表随机试验的 Cochrane 系统评价。
BJU Int. 2011 Nov;108(10):1556-63. doi: 10.1111/j.1464-410X.2011.10629.x. Epub 2011 Sep 27.
10
Atypical presentations and rare metastatic sites of renal cell carcinoma: a review of case reports.肾细胞癌的非典型表现及罕见转移部位:病例报告综述
J Med Case Rep. 2011 Sep 2;5:429. doi: 10.1186/1752-1947-5-429.