Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.
Cell Rep Methods. 2022 Nov 21;2(11):100349. doi: 10.1016/j.crmeth.2022.100349.
Technologies to reprogram somatic cells into iPSCs have advanced significantly, however challenges to the derivation of iPSCs remain. In this issue of , Kunitomi et al. address some of these challenges by developing a straightforward protocol to derive naive human iPSCs using Sendai virus vectors.
体细胞重编程为 iPS 细胞的技术已经取得了显著进展，然而，iPS 细胞的诱导仍然存在挑战。在本期杂志中，Kunitomi 等人通过开发一种使用 Sendai 病毒载体诱导原始人类 iPS 细胞的简单方案，解决了其中的一些挑战。
