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超声引导下重度创伤性脑损伤患者的脑复苏

Ultrasound-guided cerebral resuscitation in patients with severe traumatic brain Injury.

作者信息

Tamagnone Francisco Marcelo, Cheong Issac, Luna Ezequiel, Previgliano Ignacio, Otero Castro Victoria

机构信息

Argentinian Critical Care Ultrasonography Association (ASARUC), Buenos Aires, Argentina.

Department of critical care medicine, Sanatorio De los Arcos, Buenos Aires, Argentina.

出版信息

J Clin Monit Comput. 2023 Apr;37(2):359-363. doi: 10.1007/s10877-022-00954-7. Epub 2022 Dec 1.

Abstract

Traumatic brain injury (TBI) is a worldwide public health concern given its significant morbidity and mortality, years of potential life lost, reduced quality of life and elevated healthcare costs. The primary injury occurs at the moment of impact, but secondary injuries might develop as a result of brain hemodynamic abnormalities, hypoxia, and hypotension. The cerebral edema and hemorrhage of the injured tissues causes a decrease in cerebral perfusion pressure (CPP), which leads to higher risk of cerebral ischemia, herniation and death. In this setting, our role as physicians is to minimize damage by the optimization of the CPP and therefore to reduce mortality and improve neurological outcomes. Performing a transcranial doppler ultrasound (TCD) allows to estimate cerebral blood flow velocities and identify states of low flow and high resistance. We propose to include TCD as an initial assessment and further monitoring tool for resuscitation guidance in patients with severe TBI. We present an Ultrasound-Guided Cardio-cerebral Resuscitation (UGCeR) protocol in Patients with Severe TBI.

摘要

创伤性脑损伤(TBI)因其显著的发病率和死亡率、潜在生命年损失、生活质量下降以及医疗成本上升,成为全球公共卫生关注的问题。原发性损伤发生在撞击瞬间,但继发性损伤可能因脑血流动力学异常、缺氧和低血压而发展。受伤组织的脑水肿和出血导致脑灌注压(CPP)降低,从而增加脑缺血、脑疝和死亡的风险。在这种情况下,我们作为医生的职责是通过优化CPP来尽量减少损伤,从而降低死亡率并改善神经功能结局。进行经颅多普勒超声(TCD)检查可以估计脑血流速度,并识别低血流和高阻力状态。我们建议将TCD作为重度TBI患者复苏指导的初始评估和进一步监测工具。我们提出了一种针对重度TBI患者的超声引导心肺脑复苏(UGCeR)方案。

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