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脊髓刺激器感染的综合综述

A Comprehensive Review of Spinal Cord Stimulator Infections.

作者信息

Cherkalin Denis, Koushik Sarang S, Dua Simran, Rahman Sadiq, Edmonds Timothy, Gritsenko Karina, Shaparin Naum

机构信息

Montefiore Medical Center, Albert Einstein School of Medicine, Bronx, NY, USA.

Valleywise Health Medical Center, Creighton University School of Medicine Phoenix, Phoenix, AZ, USA.

出版信息

Curr Pain Headache Rep. 2022 Dec;26(12):877-882. doi: 10.1007/s11916-022-01090-2. Epub 2022 Dec 1.

Abstract

Spinal cord stimulator (SCS) is approved to treat various pain conditions and is commonly seen in the chronic pain patient population. Due to the nature of the device and its location, infections associated with SCS have a particularly high morbidity. According to post-market data and medical device reports, 87% of patients receiving SCS implants were given perioperative antibiotics as the implantable neurostimulator or receiver pocket serve as the most common sites of infection. The most common antibiotics for surgical prophylaxis given are first-generation cephalosporins (cefalexin, cefazolin) at the time of implantation. If deep infection is suspected, imaging in the form of CT scan should be obtained as physical exam is not always sufficient. For infections involving the epidural space, vertebra, or intervertebral discs, MRI is the preferred imaging modality. If meningitis is suspected, a lumbar puncture is recommended. Positive cultures can help guide antibiotic therapy.

摘要

脊髓刺激器(SCS)已被批准用于治疗各种疼痛病症,在慢性疼痛患者群体中很常见。由于该设备的性质及其位置,与SCS相关的感染发病率特别高。根据上市后数据和医疗器械报告,接受SCS植入的患者中有87%在围手术期使用了抗生素,因为可植入神经刺激器或接收器囊袋是最常见的感染部位。植入时用于手术预防的最常见抗生素是第一代头孢菌素(头孢氨苄、头孢唑林)。如果怀疑有深部感染,由于体格检查并不总是足够的,应进行CT扫描形式的成像检查。对于涉及硬膜外间隙、椎体或椎间盘的感染,MRI是首选的成像方式。如果怀疑有脑膜炎,建议进行腰椎穿刺。阳性培养结果有助于指导抗生素治疗。

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