Emerg Infect Dis. 2023 Jan;29(1):184-188. doi: 10.3201/eid2901.221293. Epub 2022 Dec 1.
Since June 2020, the SARS-CoV-2 Immunity and Reinfection Evaluation (SIREN) study has conducted routine PCR testing in UK healthcare workers and sequenced PCR-positive samples. SIREN detected increases in infections and reinfections and delected Omicron subvariant waves emergence contemporaneous with national surveillance. SIREN's sentinel surveillance methods can be used for variant surveillance.
自 2020 年 6 月以来,SARS-CoV-2 免疫和再感染评估(SIREN)研究一直在英国医护人员中进行常规 PCR 检测,并对 PCR 阳性样本进行测序。SIREN 检测到感染和再感染的增加,并与国家监测同时检测到奥密克戎亚变体波的出现。SIREN 的哨点监测方法可用于变体监测。