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利用多元统计和空间评估对土耳其黑海食用鱼类中有害微量元素积累进行毒理学健康风险分析。

Toxicological health risk analysis of hazardous trace elements accumulation in the edible fish species of the Black Sea in Türkiye using multivariate statistical and spatial assessment.

作者信息

Kalipci Erkan, Cüce Hüseyin, Ustaoğlu Fikret, Dereli Mehmet Ali, Türkmen Mustafa

机构信息

Deparment of Geomatics Engineering, Giresun University, Giresun 28200, Türkiye.

Deparment of Geomatics Engineering, Giresun University, Giresun 28200, Türkiye.

出版信息

Environ Toxicol Pharmacol. 2023 Jan;97:104028. doi: 10.1016/j.etap.2022.104028. Epub 2022 Nov 28.

DOI:10.1016/j.etap.2022.104028
PMID:36455837
Abstract

In the current study, the levels of eleven hazardous trace elements (HTEs) were measured in five different fish species frequently consumed in eleven cities along the Black Sea coast of Türkiye. And also the maximum permissible limits (MPLs) specified by international standards are compared to 11 HTEs levels. In addition, human health risk levels from fish consumption were assessed using multiple approaches. The highest metal concentrations of Fe, Mn, Co, Cr, Ni, Cd and Hg were detected in the fish sampled from Samsun city. It was determined that Cu, Zn, Pb and As metal concentrations were the highest in fish sampled from Düzce city. In the demersal Mullus barbatus (MB), the highest quantities of As, Cr, Mn, Fe, Co, Ni, Hg, and Pb were discovered. The highest concentrations of Zn and Cd were found in Engraulis encrasicolus (EE), which is a topminnow fish. The highest concentrations of Cu were found in Sarda sarda (SS), which is a topminnow fish. For all HTEs, the metal hazard index (MPI) and target hazard quotients (THQ) from metal intake by ingesting fish species were less than 1, indicating no risk from consumption. All investigated fish species were acceptable (10 to 10) in terms of carcinogenic risks (CR) from exposure to inorganic arsenic (As). Additionally, because the hazard index (HI) is less than 1, it has been determined that consuming certain fish species will not pose a risk to public health. The predicted daily intakes of HTEs in each fish species were far lower than their corresponding acceptable daily intakes, indicating that consuming fish would not put consumers at risk for health problems from daily intakes of HTEs. In addition, the multivariate statistical analysis justified that HTEs were from anthropogenic and lithogenic origin.

摘要

在当前的研究中,对土耳其黑海沿岸11个城市经常食用的5种不同鱼类中的11种有害微量元素(HTEs)水平进行了测量。并且还将国际标准规定的最大允许限量(MPLs)与11种HTEs水平进行了比较。此外,使用多种方法评估了食用鱼类对人类健康的风险水平。在从萨姆松市采集的鱼类样本中检测到铁、锰、钴、铬、镍、镉和汞的最高金属浓度。确定在从杜兹耶市采集的鱼类样本中铜、锌、铅和砷的金属浓度最高。在底栖的条尾鲱鲤(MB)中,发现了最高含量的砷、铬、锰、铁、钴、镍、汞和铅。在沙丁鱼(EE)(一种米诺鱼)中发现了最高浓度的锌和镉。在沙丁鱼(SS)(一种米诺鱼)中发现了最高浓度的铜。对于所有HTEs,通过食用鱼类摄入金属的金属危害指数(MPI)和目标危害商(THQ)均小于1,表明食用无风险。就接触无机砷(As)的致癌风险(CR)而言,所有调查的鱼类品种都是可接受的(10至10)。此外,由于危害指数(HI)小于1,已确定食用某些鱼类品种不会对公众健康构成风险。每种鱼类中HTEs的预测每日摄入量远低于其相应的可接受每日摄入量,表明食用鱼类不会使消费者因每日摄入HTEs而面临健康问题风险。此外,多元统计分析证明HTEs来自人为和岩石成因。

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