School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China.
Asia Pac J Clin Oncol. 2023 Aug;19(4):439-457. doi: 10.1111/ajco.13901. Epub 2022 Dec 1.
Over the past decade, the number of cancer cases has continued to rise, placing a heavy burden on patients' families and healthcare systems. Although innovative treatments and drugs have improved patient outcomes, the financial toxicity (FT) of treatment is a growing concern among oncologists. Previous research have examined the impacts of FT on the HRQOL of cancer patients. However, the extent of the association is unclear, given that previous studies vary in the enrolled population, adjustment of confounding factors, and usage of FT assessment tools. To address this gap, the main purpose of this systematic review is to examine the relationship between FT and HRQOL of cancer survivors, and explore any potential factors that may affect this relationship.
在过去的十年中,癌症病例的数量持续上升,给患者家庭和医疗体系带来了沉重的负担。尽管创新的治疗方法和药物改善了患者的预后,但治疗的财务毒性(FT)仍是肿瘤学家关注的一个日益严重的问题。先前的研究已经考察了 FT 对癌症患者 HRQOL 的影响。然而,由于先前的研究在入组人群、混杂因素的调整以及 FT 评估工具的使用方面存在差异,因此这种关联的程度尚不清楚。为了解决这一差距,本系统综述的主要目的是考察 FT 与癌症幸存者 HRQOL 之间的关系,并探讨可能影响这种关系的任何潜在因素。