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比较脉冲染料激光与脉冲染料激光联合CO治疗鲜红斑痣的疗效。

Comparing the therapeutic effect of pulsed dye laser and pulsed dye laser plus CO in port wine stain.

作者信息

Sheng Hao, Zeng Hui, Zhang Meng

机构信息

Department of Dermatology, Wuhan Puren Hospital, Qingshan District, Wuhan, Hubei Province, China.

Outpatient Department of Wuhan Mental Health Centre, Jiang'an District, Wuhan, Hubei Province, China.

出版信息

Postepy Dermatol Alergol. 2022 Oct;39(5):923-927. doi: 10.5114/ada.2022.119073. Epub 2022 Sep 6.

Abstract

INTRODUCTION

One of the most common congenital vascular abnormalities in the dermal area of the skin is the port-wine stain (PWS).

AIM

Researchers are trying to introduce more effective new methods of treatment of PWS.

MATERIAL AND METHODS

This clinical trial study was conducted on 60 patients in Huanggang Central Hospital during May 2020 to June 2021. Pulsed dye laser (PDL) only and PDL plus CO2 methods were used to treat PWS, the clearance scores of patients were assessed for both methods, and the side effects were examined.

RESULTS

The mean age of the patients was 26.87 ±9.67 years. The majority of the patients (80%) were female. Thirty-four (56.66%) patients had PWS in the malar area, 14 (23.33%) on their forehead, 5 (8.33%) on their chin, and 7 (11.7%) on neck. The efficacy of the treatment through clearance score shows that the quantitative mean of the clearance score of the patients in the PDL method was 2.71 ±0.54, and in the CO2 + PDL method it was 2.72 ±0.56 ( > 0.05). The qualitative comparison of clearance scores indicated that in the PDL method, 18 (30%) patients had acceptable clearance, 30 (50%) patients had good clearance, and 12 (20%) patients had excellent clearance. Also, for the PDL plus CO method, 25 (41.766) patients had acceptable clearance, 23 (38.34%) patients had good clearance, and 12 (20%) patients had excellent clearance.

CONCLUSIONS

For PWS patients under treatment with PDL plus CO, the hyperpigmentation side effect was greater than in patients with underlying PDL only.

摘要

引言

皮肤真皮层最常见的先天性血管异常之一是葡萄酒色斑(PWS)。

目的

研究人员正试图引入更有效的PWS治疗新方法。

材料与方法

2020年5月至2021年6月期间,在黄冈市中心医院对60例患者进行了这项临床试验研究。采用单纯脉冲染料激光(PDL)和PDL联合CO2方法治疗PWS,评估两种方法患者的清除率评分,并检查副作用。

结果

患者的平均年龄为26.87±9.67岁。大多数患者(80%)为女性。34例(56.66%)患者的PWS位于颧部,14例(23.33%)在前额,5例(8.33%)在下巴,7例(11.7%)在颈部。通过清除率评分评估治疗效果显示,PDL方法患者清除率评分的定量平均值为2.71±0.54,CO2+PDL方法为2.72±0.56(>0.05)。清除率评分的定性比较表明,PDL方法中,18例(30%)患者清除效果可接受,30例(50%)患者清除效果良好,12例(20%)患者清除效果极佳。同样,对于PDL联合CO方法,25例(41.766)患者清除效果可接受,23例(38.34%)患者清除效果良好,12例(20%)患者清除效果极佳。

结论

对于接受PDL联合CO治疗的PWS患者,色素沉着副作用比仅接受基础PDL治疗的患者更大。

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Nonvascular uses of pulsed dye laser in clinical dermatology.脉冲染料激光在临床皮肤科的非血管性应用。
J Cosmet Dermatol. 2019 Oct;18(5):1186-1201. doi: 10.1111/jocd.12924. Epub 2019 Apr 19.
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Glaucoma in children with facial port wine stain.患有面部葡萄酒色斑的儿童青光眼。
Eur J Ophthalmol. 2020 Jan;30(1):168-174. doi: 10.1177/1120672118819668. Epub 2018 Dec 19.

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