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2019冠状病毒病感染者的精神和神经精神问题:一项来自印度的病例对照在线研究——新现实主义研究

Psychiatric and neuropsychiatric issues in persons with COVID-19 infection: A case-control online study from India-Neorealist study.

作者信息

Vaishnav Mrugesh, Grover Sandeep, Vaishnav Parth, Sharma Kamal, Avasthi Ajit

机构信息

Director, Samvedana Happiness Hospital, Ahmedabad, Gujarat, India.

Department of Psychiatry, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Indian J Psychiatry. 2022 Sep-Oct;64(5):473-483. doi: 10.4103/indianjpsychiatry.indianjpsychiatry_303_22. Epub 2022 Oct 12.

DOI:10.4103/indianjpsychiatry.indianjpsychiatry_303_22
PMID:36458084
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9707660/
Abstract

BACKGROUND

Many studies across the globe have evaluated the adverse mental health consequences of COVID-19 in patients who suffered from COVID-19 infection. However, a comparative study of persons who suffered from COVID-19 infection and those who witnessed the COVID-19 infection in their close relatives is lacking.

AIMS AND OBJECTIVES

This study aims to compare the psychiatric morbidity in persons who suffered from COVID-19 infections, and those who witnessed the illness in one of their close relatives.

METHODS

In this cross-sectional online survey, 2,964 adult participants completed the Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7) Scale, Fear of COVID-19 Scale (FCS-19), Brief Resilient Coping Scale (BRCS), The Brief Resilience Scale (BRS) and a self-designed questionnaire to evaluate other neuropsychiatric complications.

RESULTS

Compared to the close relatives who had witnessed COVID-19 infection, participants who developed COVID-19 infection had a significantly higher prevalence of depression (34.6%), anxiety disorder (32.3%), and fear of COVID-19 infection (18.8%), which was significantly higher than that noted in close relatives. However, BRS coping score was not significantly different between the two groups. Overall, about one-third of the participants who developed COVID-19 infection had depression and one-third had anxiety disorders. One-fifth of the participants reported high fear, post-traumatic symptoms, and obsessive-compulsive symptoms, whereas one-sixth reported other neuropsychiatric manifestations.

CONCLUSION

Patients who suffered from COVID-19 have a higher prevalence of depression, anxiety, and fear as compared to those to witnessed COVID-19 in relatives.

摘要

背景

全球许多研究评估了感染新冠病毒疾病(COVID-19)患者的心理健康不良后果。然而,缺乏对感染COVID-19的患者与在其近亲中目睹COVID-19感染情况的人员的比较研究。

目的

本研究旨在比较感染COVID-19的人员与在其近亲中目睹该疾病的人员的精神疾病发病率。

方法

在这项横断面在线调查中,2964名成年参与者完成了患者健康问卷-9(PHQ-9)、广泛性焦虑障碍-7(GAD-7)量表、对COVID-19的恐惧量表(FCS-19)、简短弹性应对量表(BRCS)、简短复原力量表(BRS)以及一份自行设计的问卷,以评估其他神经精神并发症。

结果

与目睹COVID-19感染情况的近亲相比,感染COVID-19的参与者中抑郁症(34.6%)、焦虑症(32.3%)和对COVID-19感染的恐惧(18.8%)的患病率显著更高,明显高于其近亲中的患病率。然而,两组之间的BRS应对得分没有显著差异。总体而言,约三分之一感染COVID-19的参与者患有抑郁症,三分之一患有焦虑症。五分之一的参与者报告有高度恐惧、创伤后症状和强迫症状,而六分之一的参与者报告有其他神经精神表现。

结论

与在亲属中目睹COVID-19感染情况的人员相比,感染COVID-19的患者中抑郁症、焦虑症和恐惧的患病率更高。

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