Department of Urology, San Bassiano Hospital, Bassano del Grappa, Vicenza, Italy.
Department of Urology, University of Verona, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.
Urolithiasis. 2022 Dec 2;51(1):7. doi: 10.1007/s00240-022-01382-7.
Urolithiasis is a worldwide spread condition that affects patients' Health-Related Quality of Life (HRQOL), which measurement is an important tool for routine clinical and research practice. Disease-specific HRQOL measures demonstrated to perform better in assessing the effects of specific conditions. A disease-specific questionnaire for kidney stones, the WISQOL, has been validated in different languages, but an Italian version is still missing. Our aim is to produce and validate the Italian version of WISQOL (IT-WISQOL). Patients undergoing any elective treatment for upper urinary tract stones were enrolled. A multi-step process with forward- and back-translation was used to translate WISQOL into Italian. Patients were evaluated within 15 days pre-operatively and then at 30-, 90 days post-operatively and administered both IT-WISQOL and SF-36v2. Post-operative data such as 30 days postoperative complications, late stone-related events, successful status, and stone complexity were collected. Cronbach's α was used to evaluate the internal consistency of IT-WISQOL, while Spearman's rho was used for item and inter-domain correlations and IT-WISQOL with SF-36v2 correlation. We found excellent internal consistency across all domains (α ≥ 0.88), particularly when the total score is considered (α = 0.960). Test-retest reliability showed excellent results for the total questionnaire (Pearson correlation value: 0.85). The Inter-domain association ranged from 0.497 to 0.786. Convergent validity was confirmed by a good correlation with subdomains of the SF-36v2 measures. IT-WISQOL is a reliable tool to measure HRQOL in stone patients. It shows analog characteristics if compared to English WISQOL.
尿石症是一种全球范围内的疾病，影响患者的健康相关生活质量（HRQOL），其测量是常规临床和研究实践的重要工具。针对特定疾病的 HRQOL 测量方法在评估特定疾病的效果方面表现更优。一种针对肾结石的特定疾病问卷，WISQOL，已在多种语言中得到验证，但仍缺少意大利语版本。我们的目标是生成并验证 WISQOL 的意大利语版本（IT-WISQOL）。纳入接受任何选择性上尿路结石治疗的患者。采用正向和反向翻译的多步骤过程将 WISQOL 翻译成意大利语。患者在术前 15 天内进行评估，然后在术后 30 天和 90 天进行评估，并同时使用 IT-WISQOL 和 SF-36v2 进行评估。收集术后数据，如 30 天术后并发症、晚期结石相关事件、成功状态和结石复杂性。使用 Cronbach's α 评估 IT-WISQOL 的内部一致性，使用 Spearman's rho 评估项目和域间相关性以及 IT-WISQOL 与 SF-36v2 的相关性。我们发现所有域的内部一致性都非常好（α≥0.88），尤其是当考虑总分为零时（α=0.960）。测试-重测信度显示整个问卷的结果非常好（Pearson 相关值：0.85）。域间关联范围为 0.497 至 0.786。与 SF-36v2 测量的子域的良好相关性证实了收敛有效性。IT-WISQOL 是一种可靠的工具，可用于测量结石患者的 HRQOL。与英语 WISQOL 相比，它具有类似的特征。
