School of Environment, Henan Key Laboratory for Environmental Pollution Control, Key Laboratory for Yellow River and Huai River Water Environment and Pollution Control, Ministry of Education, Henan Normal University, Xinxiang, Henan 453007, PR China; School of Chemistry & Materials Engineering, Xinxiang University, Xinxiang, Henan 453003, PR China.
School of Environment, Henan Key Laboratory for Environmental Pollution Control, Key Laboratory for Yellow River and Huai River Water Environment and Pollution Control, Ministry of Education, Henan Normal University, Xinxiang, Henan 453007, PR China.
Food Chem. 2023 Apr 16;406:135060. doi: 10.1016/j.foodchem.2022.135060. Epub 2022 Nov 28.
Antioxidants, widely utilized in the food packaging field, have a risk of migrating into foodstuffs and eventually entering the human body. In this work, a novel method was established for green extraction and determination of antioxidants in food simulants migrated from plastic packaging materials. It was found that the antioxidants could be extracted directly from food simulants by in-situ formation of hydrophobic deep eutectic solvents with low toxic medium-chain fatty alcohols. Under the optimal conditions, the limit of detection was 0.15 to 0.25 µg/L, and the limit of quantification was 0.5 to 1.0 µg/L for the antioxidants. The extraction reaches equilibrium in 2 min. Importantly, butylated hydroxytoluene was detected in two types of the surveyed food contact materials. The established method shows high sensitivity, high enrichment factor, and strong anti-interference ability, and can be used for the separation and enrichment of ultra-trace antioxidants in foodstuffs.
抗氧化剂广泛应用于食品包装领域，但存在向食品迁移并最终进入人体的风险。在这项工作中，建立了一种从塑料包装材料迁移到食品模拟物中的抗氧化剂的绿色提取和测定的新方法。研究发现，抗氧化剂可以通过原位形成具有低毒性的中链脂肪酸醇的疏水性深共晶溶剂直接从食品模拟物中提取。在最佳条件下，抗氧化剂的检出限为 0.15-0.25μg/L，定量限为 0.5-1.0μg/L。萃取在 2 分钟内达到平衡。重要的是，在两种调查的食品接触材料中检测到了丁基羟基甲苯。所建立的方法具有灵敏度高、富集因子高、抗干扰能力强的特点，可用于食品中超痕量抗氧化剂的分离和富集。
