Kandulu Hüseyin
Huseyin Kandulu Clinic for Plastic Surgery, Teşvikiye, Terrace Fulya Teşvikiye Mah. Hakkı Yeten Cad.No.13 Center 1 Kat 11 D.59, Istanbul, Turkey.
Aesthetic Plast Surg. 2023 Apr;47(2):685-689. doi: 10.1007/s00266-022-03098-w. Epub 2022 Dec 6.
The presence of obesity with dyslipidemia is a worldwide health problem and one of the major risks for cardiovascular diseases. The metabolic effects of liposuction are being investigated in terms of insulin resistance and reducing cholesterol levels. We aimed to examine the metabolic effects of Vibration Amplification of Sound Energy at Resonance (VASER)-assisted liposuction on the lipid profiles of overweight patients.
Eighteen patients who underwent VASER-assisted liposuction were investigated in terms of changes in lipid profiles. The total cholesterol (Total-C), triglycerides (TGs), Low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) levels were measured enzymatically. We also calculated Non-HDL Cholesterol levels and Total Cholesterol/HDL Cholesterol ratios.
We observed that Total-C (p ≤ 0.0001), LDL-C (p ≤ 0.0001), TGs (p = 0.0004), Non-HDL-C levels (p ≤ 0.0001) and Total-C/HDL-C ratios (p ≤ 0.0001) decreased on the third month after VASER-assisted liposuction.
We conclude that VASER-assisted liposuction could be beneficial to regulate lipid metabolism. Especially, decrements of Non-HDL Cholesterol and Total-C/HDL-C ratio could be protective against cardiovascular diseases.
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肥胖伴血脂异常是一个全球性的健康问题,也是心血管疾病的主要风险之一。抽脂术对代谢的影响正从胰岛素抵抗和降低胆固醇水平方面进行研究。我们旨在研究共振声能放大(VASER)辅助抽脂术对超重患者血脂谱的代谢影响。
对18例行VASER辅助抽脂术的患者的血脂谱变化进行了研究。采用酶法测定总胆固醇(Total-C)、甘油三酯(TGs)、低密度脂蛋白胆固醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C)水平。我们还计算了非高密度脂蛋白胆固醇水平和总胆固醇/高密度脂蛋白胆固醇比值。
我们观察到,VASER辅助抽脂术后第三个月,Total-C(p≤0.0001)、LDL-C(p≤0.0001)、TGs(p = 0.0004)、非高密度脂蛋白胆固醇水平(p≤0.0001)和总胆固醇/高密度脂蛋白胆固醇比值(p≤0.0001)均下降。
我们得出结论,VASER辅助抽脂术可能有助于调节脂质代谢。特别是,非高密度脂蛋白胆固醇和总胆固醇/高密度脂蛋白胆固醇比值的降低可能对心血管疾病具有保护作用。
证据水平IV:本刊要求作者为每篇文章指定一个证据水平。有关这些循证医学评级的完整描述,请参阅目录或作者在线指南www.springer.com/00266 。