乳腺小叶病变的最新进展。
Update on lobular lesions of the breast.
机构信息
Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
出版信息
Histopathology. 2023 Jan;82(1):36-52. doi: 10.1111/his.14829.
Abstract
The current histological classification of in-situ and invasive lobular carcinomas (ILCs) includes different morphological variants, some of which have been recently described. In this review, we will focus upon: (i) the diagnostic criteria of non-invasive lobular neoplasia and treatment implications across different countries; (ii) utility and limitations of immunohistochemistry; (iii) recently described variants of ILC; and (iv) the significance of lobular differentiation in invasive carcinoma for clinical management.
摘要
当前原位和浸润性小叶癌（ILC）的组织学分类包括不同的形态学变体，其中一些最近已经被描述。在这篇综述中，我们将重点关注：（i）不同国家的非浸润性小叶肿瘤的诊断标准和治疗意义；（ii）免疫组织化学的应用和局限性；（iii）最近描述的 ILC 变体；以及（iv）浸润性癌中小叶分化对临床管理的意义。
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