Department of Psychiatry, Laboratory of Psychiatric Research (ULB 266), Cliniques Universitaires de Bruxelles, Université Libre de Bruxelles (ULB), 1070 Bruxelles, Belgium.
Department of Child Psychiatry, Laboratory of Psychiatric Research (ULB 266), Cliniques Universitaires de Bruxelles, Université Libre de Bruxelles (ULB), 1070 Bruxelles, Belgium.
Int J Environ Res Public Health. 2022 Dec 2;19(23):16147. doi: 10.3390/ijerph192316147.
The aim of the study was to explore in depression the relationship between recent suicidal ideation and the different anhedonias taking into account the severity of depression. Recent studies have suggested that recent change of anhedonia and not state or trait anhedonia is associated with recent suicidal ideations even when the level of depression is controlled. Three samples were used (74 severe major depressives, 43 outpatients with somatic disorders presenting mild or moderate depression and 36 mild or moderate depressives hospitalized in the intensive coronary unit). Recent change of anhedonia was rated by the anhedonia subscale of the Beck Depression Inventory (BDI-II), state anhedonia by the Snaith-Hamilton Pleasure Scale (SHAPS), trait anhedonia by the TEPS (Temporal Experience of Pleasure Scale), musical anhedonia by the BMRQ (Barcelona Music Reward Questionnaire), social recent change of anhedonia by the SLIPS (Specific Loss of Interest and Pleasure Scale), the severity of depression by the BDI-II and the distinction between melancholic and non-melancholic was found using a subscale of the BDI-II. Bivariate and multivariate regression analyses were performed in each sample. In severe major depressives and, notably, in melancholia, recent suicidal ideation was associated with trait anhedonia; however, in mild or moderate depression, recent suicidal ideation was associated with recent change of anhedonia. Musical anhedonia and social recent change of anhedonia were not associated with recent suicidal ideation. Trait anhedonia could be, in severe depression, a strong predictor of recent suicidal ideation.
本研究旨在探讨抑郁患者中，近期自杀意念与不同快感缺失之间的关系，同时考虑到抑郁的严重程度。近期研究表明，即使在控制抑郁程度的情况下，快感缺失的近期变化而不是状态或特质快感缺失与近期自杀意念有关。本研究使用了三个样本（74 名严重抑郁症患者、43 名患有轻度或中度抑郁的躯体疾病门诊患者和 36 名在强化冠心病单元住院的轻度或中度抑郁症患者）。近期快感缺失的变化通过贝克抑郁量表（BDI-II）的快感缺失子量表进行评估，状态快感缺失通过 Snaith-Hamilton 快感量表（SHAPS）进行评估，特质快感缺失通过 TEPS（时间体验快感量表）进行评估，音乐快感缺失通过 BMRQ（巴塞罗那音乐奖励问卷）进行评估，社会近期快感缺失变化通过 SLIPS（特定兴趣和快感丧失量表）进行评估，抑郁的严重程度通过 BDI-II 进行评估，忧郁症和非忧郁症的区别使用 BDI-II 的一个子量表进行评估。在每个样本中都进行了双变量和多变量回归分析。在严重抑郁症患者中，特别是在忧郁症中，近期自杀意念与特质快感缺失有关；然而，在轻度或中度抑郁症中，近期自杀意念与近期快感缺失的变化有关。音乐快感缺失和社会近期快感缺失变化与近期自杀意念无关。在严重抑郁中，特质快感缺失可能是近期自杀意念的一个强有力的预测因素。
