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产妇围产期抑郁症发生时间对婴儿18个月时社会和情感发展的影响。

Impact of the Timing of Maternal Peripartum Depression on Infant Social and Emotional Development at 18 Months.

作者信息

Wendland Jaqueline, Benarous Xavier, Young Héloïse, Brahim Takoua, Apter Gisèle, Bodeau Nicolas, Cohen David, Gérardin Priscille

机构信息

Psychopathology and Health Processes Laboratory, Institute of Psychology, University Paris Cité, 92774 Boulogne Billancourt, France.

Department of Child and Adolescent Psychiatry, Pitié-Salpêtrière University Hospital, Assistance Publique-Hôpitaux de Paris, 75013 Paris, France.

出版信息

J Clin Med. 2022 Nov 23;11(23):6919. doi: 10.3390/jcm11236919.

DOI:10.3390/jcm11236919
PMID:36498494
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9735611/
Abstract

The study assessed how the timing of maternal perinatal depressive symptoms affects infant socio-emotional characteristics at age 18 months. The study was a longitudinal cohort study that included six assessment points from the third trimester of pregnancy up to age 18 months (±1 month). Assessment of mothers included the Edinburgh Postnatal Depression Scale and the State-Trait Anxiety Inventory, while assessments of infant included the Infant Toddler Social and Emotional Assessment (ITSEA) at 18 months. Mothers were categorized into one of the following groups: mothers who presented postnatal depression only ( = 19); mothers who presented both prenatal and postnatal depression ( = 14), and mothers who never showed perinatal depression symptoms ( = 38). Mothers who presented both prenatal and postnatal depression showed significantly higher levels of depressive score, reactivity to stress and level of anxiety trait compared to mothers of the two other groups. Infants of prenatally and postnatally depressed mothers had higher scores on the internalizing subscore of the ITSEA. The number of depression episodes during the study period was positively correlated with the externalizing and internalizing subscores of the ITSEA. These findings support the need to provide specific screening to identify women with prenatal depression.

摘要

该研究评估了母亲围产期抑郁症状的发生时间如何影响婴儿18个月大时的社会情感特征。该研究是一项纵向队列研究,包括从妊娠晚期到18个月大(±1个月)的六个评估点。对母亲的评估包括爱丁堡产后抑郁量表和状态-特质焦虑量表,而对婴儿的评估包括18个月时的婴幼儿社会和情感评估(ITSEA)。母亲被分为以下几组之一:仅出现产后抑郁的母亲(n = 19);同时出现产前和产后抑郁的母亲(n = 14),以及从未出现围产期抑郁症状的母亲(n = 38)。与其他两组母亲相比,同时出现产前和产后抑郁的母亲表现出显著更高的抑郁评分、应激反应性和特质焦虑水平。产前和产后抑郁母亲的婴儿在ITSEA内化子量表上得分更高。研究期间抑郁发作的次数与ITSEA的外化和内化子量表呈正相关。这些发现支持了进行特定筛查以识别产前抑郁女性的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15ed/9735611/d4bcac14ebd8/jcm-11-06919-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15ed/9735611/d4bcac14ebd8/jcm-11-06919-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15ed/9735611/d4bcac14ebd8/jcm-11-06919-g001.jpg

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Maternal Distress and Offspring Neurodevelopment: Challenges and Opportunities for Pre-clinical Research Models.母体应激与子代神经发育:临床前研究模型面临的挑战与机遇
Front Hum Neurosci. 2021 Feb 12;15:635304. doi: 10.3389/fnhum.2021.635304. eCollection 2021.
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Identifying trajectories of antenatal depression in women and their associations with gestational age and neonatal anthropometry: A prospective cohort study.
识别孕妇抑郁的轨迹及其与胎龄和新生儿人体测量的关联:一项前瞻性队列研究。
Gen Hosp Psychiatry. 2019 Nov-Dec;61:26-33. doi: 10.1016/j.genhosppsych.2019.09.001. Epub 2019 Sep 12.
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Maternal prenatal depressive symptoms and risk for early-life psychopathology in offspring: genetic analyses in the Norwegian Mother and Child Birth Cohort Study.母亲产前抑郁症状与后代早期精神病理学风险:挪威母婴队列研究中的基因分析
Lancet Psychiatry. 2018 Oct;5(10):808-815. doi: 10.1016/S2215-0366(18)30225-6. Epub 2018 Sep 20.
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