Gotmare Swati Shrikant, Babu Cathy, Shetty Subraj, Pereira Treville
Department of Oral and Maxillofacial Pathology, D Y Patil University School of Dentistry, Navi Mumbai, Maharashtra, India.
J Microsc Ultrastruct. 2021 Sep 8;10(3):143-145. doi: 10.4103/jmau.jmau_96_20. eCollection 2022 Jul-Sep.
Adenoid cystic carcinoma (ACC) is an unusual slow growing salivary gland malignancy with higher chances of recurrence. It is characterized by the proliferation of ductal (luminal) and myoepithelial cells in cribriform, tubular, solid, and cystic forms. Standard treatment, including surgery with postoperative radiation therapy, has attained reasonable local control rates, but distant metastases do not allow any improvement in the survival rate. We present a case of a 50-year-old female diagnosed with ACC involving almost the whole of the upper lip, with an aim to highlight its histologic evolution from it being clinically seen as severely ulcerated and necrotised upper lip mimicking a case of squamous cell carcinoma and its prognosis.
腺样囊性癌(ACC)是一种罕见的生长缓慢的唾液腺恶性肿瘤,复发几率较高。其特征是导管(管腔)和肌上皮细胞呈筛状、管状、实性和囊性增殖。标准治疗方法,包括手术及术后放射治疗,已取得了合理的局部控制率,但远处转移使得生存率无法得到任何改善。我们报告一例50岁女性被诊断为腺样囊性癌累及几乎整个上唇的病例,旨在突出其组织学演变过程,该病例临床上最初表现为严重溃疡和坏死的上唇,类似鳞状细胞癌,同时报告其预后情况。