Wang Min, Peng Ya
Department of Cardiothoracic Surgery, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Department of Neurosurgery, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Front Mol Neurosci. 2022 Nov 24;15:1053478. doi: 10.3389/fnmol.2022.1053478. eCollection 2022.
Neurocardiology is an emerging field that studies the interaction between the brain and the heart, namely the effects of heart injury on the brain and the effects of brain damage on the heart. Acute ischemic stroke has long been known to induce heart damage. Most post-stroke deaths are attributed to nerve damage, and cardiac complications are the second leading cause of death after stroke. In clinical practice, the proper interpretation and optimal treatment for the patients with heart injury complicated by acute ischemic stroke, recently described as stroke-heart syndrome (SHS), are still unclear. Here, We describe a wide range of clinical features and potential mechanisms of cardiac complications after ischemic stroke. Autonomic dysfunction, microvascular dysfunction and coronary ischemia process are interdependent and play an important role in the process of cardiac complications caused by stroke. As a unique comprehensive view, SHS can provide theoretical basis for research and clinical diagnosis and treatment.
神经心脏病学是一个新兴领域,研究大脑与心脏之间的相互作用,即心脏损伤对大脑的影响以及脑损伤对心脏的影响。长期以来,人们一直知道急性缺血性中风会导致心脏损伤。大多数中风后死亡归因于神经损伤,而心脏并发症是中风后第二大死亡原因。在临床实践中,对于并发急性缺血性中风的心脏损伤患者(最近被称为中风-心脏综合征,SHS)的正确解读和最佳治疗仍不明确。在此,我们描述了缺血性中风后心脏并发症的广泛临床特征和潜在机制。自主神经功能障碍、微血管功能障碍和冠状动脉缺血过程相互依存,并在中风引起的心脏并发症过程中起重要作用。作为一种独特的综合观点,SHS可为研究及临床诊断和治疗提供理论依据。