Rao Yunbo, Lv Qingsong, Zeng Shaoning, Yi Yuling, Huang Cheng, Gao Yun, Cheng Zhanglin, Sun Jihong
School of Information and Software Engineering, University of Electronic Science and Technology of China, Chengdu, 611731, China.
Yangtze Delta Region Institute (Huzhou), University of Electronic Science and Technology of China, Huzhou, 313000, China.
Biomed Signal Process Control. 2023 Mar;81:104486. doi: 10.1016/j.bspc.2022.104486. Epub 2022 Dec 5.
The ground glass opacity (GGO) of the lung is one of the essential features of COVID-19. The GGO in computed tomography (CT) images has various features and low-intensity contrast between the GGO and edge structures. These problems pose significant challenges for segmenting the GGO. To tackle these problems, we propose a new threshold method for accurate segmentation of GGO. Specifically, we offer a framework for adjusting the threshold parameters according to the image contrast. Three functions include Attention mechanism threshold, Contour equalization, and Lung segmentation (ACL). The lung is divided into three areas using the attention mechanism threshold. Further, the segmentation parameters of the attention mechanism thresholds of the three parts are adaptively adjusted according to the image contrast. Only the segmentation regions restricted by the lung segmentation results are retained. Extensive experiments on four COVID datasets show that ACL can segment GGO images at low contrast well. Compared with the state-of-the-art methods, the similarity Dice of the ACL segmentation results is improved by 8.9%, the average symmetry surface distance ASD is reduced by 23%, and the required computational power are only 0.09% of those of deep learning models. For GGO segmentation, ACL is more lightweight, and the accuracy is higher. Code will be released at https://github.com/Lqs-github/ACL.
肺部磨玻璃影(GGO)是新型冠状病毒肺炎(COVID-19)的重要特征之一。计算机断层扫描(CT)图像中的GGO具有多种特征,且GGO与边缘结构之间的强度对比度较低。这些问题给GGO的分割带来了重大挑战。为了解决这些问题,我们提出了一种用于准确分割GGO的新阈值方法。具体来说,我们提供了一个根据图像对比度调整阈值参数的框架。三个功能包括注意力机制阈值、轮廓均衡和肺部分割(ACL)。利用注意力机制阈值将肺部划分为三个区域。此外,根据图像对比度自适应调整三个部分的注意力机制阈值的分割参数。只保留受肺部分割结果限制的分割区域。在四个COVID数据集上进行的大量实验表明,ACL能够很好地分割低对比度的GGO图像。与现有最先进的方法相比,ACL分割结果的相似性Dice提高了8.9%,平均对称表面距离ASD降低了23%,所需计算能力仅为深度学习模型的0.09%。对于GGO分割,ACL更轻量级,且准确性更高。代码将在https://github.com/Lqs-github/ACL上发布。