Chavarría Larisa, Quinteros Edgar, Sánchez Mario, Domínguez Rhina
Governance and Knowledge Management Unit, National Institute of Health, San Salvador, El Salvador.
Research Unit, National Institute of Health, San Salvador, El Salvador.
J Family Med Prim Care. 2022 Sep;11(9):5148-5154. doi: 10.4103/jfmpc.jfmpc_1699_21. Epub 2022 Oct 14.
Around the world 60,000 people die from rabies each year. The main form of exposure to rabies is by the bite of animals infected with the virus. More than 20,000 cases of rabies-transmitting animal bites are reported each year, in El Salvador, a country located in Central America. People exposed should be managed with rabies prophylaxis.
To determine the abandonment of post-exposure prophylaxis (PEP) cumulative incidence (CI) in humans bitten by suspected rabid animals in El Salvador from 2013 to 2017.
This is an ecological study based on the cases of bites by suspected rabid animals reported between 2013 and 2017 in the public health system of El Salvador. Descriptive and correlation analysis was performed using Statistical Package for the Social Sciences (SPSS) version 24. The municipality CI, expressed per 100,000 inhabitants.
The national CI of abandonment PEP in humans bitten by suspected rabid animals was 25.6 × 100,000 inhabitants. Simple bivariate correlation analysis shows that the departments with the highest CI of bites caused by cats, wild animals, and bites on the neck ( = 0.99 < 0.05) are mostly associated with dropping out of the PEP.
In El Salvador, the abandonment CI of PEP is lower than other countries, however, bites by rabid suspected animal are frequent, this represents a public health problem due to the presence of the rabies virus in wild animals and the high lethality of the disease. Municipalities where head bites are common are the most related to the abandonment of PEP.
全球每年有6万人死于狂犬病。感染狂犬病的主要途径是被感染病毒的动物咬伤。在中美洲国家萨尔瓦多,每年报告超过2万例可传播狂犬病的动物咬伤病例。暴露人群应接受狂犬病预防治疗。
确定2013年至2017年萨尔瓦多疑似狂犬病动物咬伤人类后暴露后预防治疗(PEP)的累计放弃发病率(CI)。
这是一项基于2013年至2017年萨尔瓦多公共卫生系统报告的疑似狂犬病动物咬伤病例的生态学研究。使用社会科学统计软件包(SPSS)24版进行描述性和相关性分析。按每10万居民计算市CI。
疑似狂犬病动物咬伤人类后放弃PEP的全国CI为每10万居民25.6例。简单双变量相关性分析表明,猫、野生动物咬伤以及颈部咬伤CI最高的部门( = 0.99 < 0.05)大多与放弃PEP有关。
在萨尔瓦多,PEP的放弃CI低于其他国家,然而,疑似狂犬病动物的咬伤很常见,由于野生动物中存在狂犬病病毒以及该疾病的高致死率,这代表了一个公共卫生问题。头部咬伤常见的市与放弃PEP的关系最为密切。