Alhaffar Mervat, Basaleem Huda, Othman Fouad, Alsakkaf Khaled, Naji Sena Mohammed Mohsen, Kolaise Hussein, Babattah Abdullah K, Salem Yassin Abdulmalik Mahyoub, Brindle Hannah, Yahya Najwa, Pepe Pasquale, Checchi Francesco
Department of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.
Department of Community Medicine and Public Health, Faculty of Medicine and Health Science, University of Aden, Aden, Yemen.
Confl Health. 2022 Dec 12;16(1):63. doi: 10.1186/s13031-022-00497-3.
Widespread armed conflict has affected Yemen since 2014. To date, the mortality toll of seven years of crisis, and any excess due to the COVID-19 pandemic, are not well quantified. We attempted to estimate population mortality during the pre-pandemic and pandemic periods in nine purposively selected urban and rural communities of southern and central Yemen (Aden and Ta'iz governorates), totalling > 100,000 people.
Within each study site, we collected lists of decedents between January 2014-March 2021 by interviewing different categories of key community informants, including community leaders, imams, healthcare workers, senior citizens and others. After linking records across lists based on key variables, we applied two-, three- or four-list capture-recapture analysis to estimate total death tolls. We also computed death rates by combining these estimates with population denominators, themselves subject to estimation.
After interviewing 138 disproportionately (74.6%) male informants, we identified 2445 unique decedents. While informants recalled deaths throughout the study period, reported deaths among children were sparse: we thus restricted analysis to persons aged ≥ 15 years old. We noted a peak in reported deaths during May-July 2020, plausibly coinciding with the first COVID-19 wave. Death rate estimates featured uninformatively large confidence intervals, but appeared elevated compared to the non-crisis baseline, particularly in two sites where a large proportion of deaths were attributed to war injuries. There was no clear-cut evidence of excess mortality during the pandemic period.
We found some evidence of a peak in mortality during the early phase of the pandemic, but death rate estimates were otherwise too imprecise to enable strong inference on trends. Estimates suggested substantial mortality elevations from baseline during the crisis period, but are subject to serious potential biases. The study highlighted challenges of data collection in this insecure, politically contested environment.
自2014年以来,广泛的武装冲突影响了也门。迄今为止,七年危机造成的死亡人数以及因新冠疫情导致的任何额外死亡人数都没有得到很好的量化。我们试图估计也门南部和中部(亚丁省和塔伊兹省)九个经过有目的选择的城乡社区在疫情前和疫情期间的人口死亡率,这些社区总人口超过10万人。
在每个研究地点,我们通过采访不同类别的关键社区信息提供者,包括社区领袖、伊玛目、医护人员、老年人等,收集了2014年1月至2021年3月期间的死亡人员名单。在根据关键变量将各名单上的记录进行关联后,我们应用两列表、三列表或四列表捕获 - 再捕获分析来估计总死亡人数。我们还通过将这些估计值与人口分母相结合来计算死亡率,而人口分母本身也需要进行估计。
在采访了138名男性比例过高(74.6%)的信息提供者后,我们确定了2445名独特的死亡者。虽然信息提供者回忆起了整个研究期间的死亡情况,但报告的儿童死亡情况很少:因此我们将分析限制在年龄≥15岁的人群。我们注意到2020年5月至7月报告的死亡人数出现峰值,这可能与第一波新冠疫情同时发生。死亡率估计值的置信区间非常大且无信息价值,但与非危机基线相比似乎有所升高,特别是在两个有很大比例死亡归因于战争伤害的地点。在疫情期间没有明确的超额死亡率证据。
我们发现了一些证据表明疫情早期死亡率出现峰值,但死亡率估计值在其他方面过于不精确,无法对趋势进行有力推断。估计表明危机期间死亡率较基线大幅升高,但存在严重的潜在偏差。该研究突出了在这个不安全、政治上存在争议的环境中数据收集的挑战。