Holekamp T L, Arribas N P, Boniuk I
Arch Ophthalmol. 1979 Jan;97(1):109-11. doi: 10.1001/archopht.1979.01020010049012.
Retinal detachment surgery and other long-duration ocular procedures can be performed safely with local anesthesia, but a long-acting anesthetic is required. A randomized and masked prospective series of 126 scleral buckling procedures was undertaken to test a mixture of bupivacaine (Marcaine), lidocaine (Xylocaine), and epinephrine against lidocaine and epinephrine. The data collected show a conclusive superiority of the bupivacaine mixture in longevity of action and overall performance. Also, there was significantly less variability in the quality of anesthesia with the mixture than with lidocaine (p = .0015).
视网膜脱离手术及其他长时间的眼科手术可在局部麻醉下安全进行,但需要长效麻醉剂。开展了一项随机、双盲前瞻性系列研究,纳入126例巩膜扣带术,以测试布比卡因(耐乐品)、利多卡因(赛罗卡因)和肾上腺素的混合物与利多卡因和肾上腺素相比的效果。收集的数据显示,布比卡因混合物在作用时长和总体表现方面具有决定性优势。此外,与利多卡因相比,该混合物麻醉质量的变异性显著更小(p = 0.0015)。