Maimon W N, Schuller D E
Arch Otolaryngol. 1984 Aug;110(8):525-8. doi: 10.1001/archotol.1984.00800340037009.
The ideal local anesthetic agent for facial plastic surgery should have rapid onset, good surgical anesthesia, and reasonably long duration. The purpose of this prospective, randomized, double-blind study was to compare 1% lidocaine hydrochloride with 1:200,000 epinephrine with 0.5% bupivacaine hydrochloride with 1:200,000 epinephrine, a newer, longer-acting local anesthetic, in different facial operations. The results suggest that bupivacaine is an effective and safe agent for these procedures.
用于面部整形手术的理想局部麻醉剂应起效迅速、具备良好的手术麻醉效果且持续时间合理。这项前瞻性、随机、双盲研究的目的是比较1%盐酸利多卡因加1:200,000肾上腺素与0.5%盐酸布比卡因加1:200,000肾上腺素(一种更新的、作用时间更长的局部麻醉剂)在不同面部手术中的效果。结果表明布比卡因是这些手术中一种有效且安全的药物。