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Exercise improves surrogate measures of liver histological response in metabolic dysfunction-associated steatotic liver disease.运动改善代谢功能障碍相关脂肪性肝病中肝组织学应答的替代指标。
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Exercise training improves serum biomarkers of liver fibroinflammation in patients with metabolic dysfunction-associated steatohepatitis.运动训练可改善代谢功能障碍相关脂肪性肝炎患者血清肝纤维化炎症生物标志物。
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本文引用的文献

1
Non-Invasive Biomarkers of Nonalcoholic Steatohepatitis: the FNIH NIMBLE project.非酒精性脂肪性肝炎的非侵入性生物标志物：美国国立卫生研究院肝脏疾病生物标志物联盟项目
Nat Med. 2022 Mar;28(3):430-432. doi: 10.1038/s41591-021-01652-8.
2
NASHFit: A randomized controlled trial of an exercise training program to reduce clotting risk in patients with NASH.NASHFit：一项针对 NASH 患者降低血栓风险的运动训练计划的随机对照试验。
Hepatology. 2022 Jul;76(1):172-185. doi: 10.1002/hep.32274. Epub 2022 Jan 22.
3
Expert Panel Review to Compare FDA and EMA Guidance on Drug Development and Endpoints in Nonalcoholic Steatohepatitis.专家小组审查，以比较美国食品药品监督管理局（FDA）和欧洲药品管理局（EMA）关于非酒精性脂肪性肝炎药物开发及终点指标的指南
Gastroenterology. 2022 Mar;162(3):680-688. doi: 10.1053/j.gastro.2021.10.051. Epub 2021 Nov 23.
4
Magnetic resonance elastography for prediction of long-term progression and outcome in chronic liver disease: A retrospective study.磁共振弹性成像预测慢性肝病的长期进展和结局：一项回顾性研究。
Hepatology. 2022 Feb;75(2):379-390. doi: 10.1002/hep.32151. Epub 2021 Dec 15.
5
Clinical utility of 30% relative decline in MRI-PDFF in predicting fibrosis regression in non-alcoholic fatty liver disease.MRI-PDFF 下降 30%对预测非酒精性脂肪性肝病纤维化消退的临床效用。
Gut. 2022 May;71(5):983-990. doi: 10.1136/gutjnl-2021-324264. Epub 2021 Apr 21.
6
Imaging biomarkers of NAFLD, NASH, and fibrosis.非酒精性脂肪性肝病、非酒精性脂肪性肝炎和纤维化的影像学生物标志物。
Mol Metab. 2021 Aug;50:101167. doi: 10.1016/j.molmet.2021.101167. Epub 2021 Jan 15.
7
Change in MRI-PDFF and Histologic Response in Patients With Nonalcoholic Steatohepatitis: A Systematic Review and Meta-Analysis.非酒精性脂肪性肝炎患者的 MRI-PDFF 和组织学应答变化：系统评价和荟萃分析。
Clin Gastroenterol Hepatol. 2021 Nov;19(11):2274-2283.e5. doi: 10.1016/j.cgh.2020.08.061. Epub 2020 Aug 31.
8
Suboptimal reliability of liver biopsy evaluation has implications for randomized clinical trials.肝活检评估的可靠性欠佳对随机临床试验有影响。
J Hepatol. 2020 Dec;73(6):1322-1332. doi: 10.1016/j.jhep.2020.06.025. Epub 2020 Jun 28.
9
Report on the AASLD/EASL Joint Workshop on Clinical Trial Endpoints in NAFLD.非酒精性脂肪性肝病临床试验终点的 AASLD/EASL 联合研讨会报告。
Hepatology. 2019 Oct;70(4):1424-1436. doi: 10.1002/hep.30782. Epub 2019 Jul 9.
10
Increased risk of mortality by fibrosis stage in nonalcoholic fatty liver disease: Systematic review and meta-analysis.非酒精性脂肪性肝病中纤维化阶段导致的死亡风险增加：系统评价与荟萃分析
Hepatology. 2017 May;65(5):1557-1565. doi: 10.1002/hep.29085. Epub 2017 Mar 31.

磁共振成像质子密度脂肪分数作为非酒精性脂肪性肝炎患者治疗反应的基于成像的生物标志物。

Magnetic resonance imaging proton density fat fraction as an imaging-based biomarker of treatment response in patients with nonalcoholic steatohepatitis.

作者信息

Stine Jonathan G, Loomba Rohit

机构信息

Division of Gastroenterology and Hepatology Department of Medicine Pennsylvania State University Milton S. Hershey Medical Center Hershey Pennsylvania USA.

Department of Public Health Sciences Pennsylvania State University Milton S. Hershey Medical Center Hershey Pennsylvania USA.

出版信息

Clin Liver Dis (Hoboken). 2022 Dec 12;20(6):198-201. doi: 10.1002/cld.1249. eCollection 2022 Dec.

DOI:10.1002/cld.1249
PMID:36523866
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9745255/
Abstract

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