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薰衣草-佛手柑精油芳香疗法与正念干预对绝经后女性性功能、焦虑和抑郁的影响:一项析因设计的随机对照试验

Effect of Aromatherapy with Essential oil of Lavandula Angustifolia Mill- Citrus Bergamia and Mindfulness-Based Intervention on Sexual Function, Anxiety, and Depression in Postmenopausal Women: A Randomized Controlled Trial with Factorial Design.

作者信息

Mojtehedi Mandana, Salehi-Pourmehr Hanieh, Ostadrahimi Alireza, Asnaashari Solmaz, Esmaeilpour Khalil, Farshbaf-Khalili Azizeh

机构信息

Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.

Neuroscience, Research Center for Evidence-based medicine, Iranian EBM Centre, A Joanna Briggs Institute (JBI) Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

Iran J Nurs Midwifery Res. 2022 Sep 14;27(5):392-405. doi: 10.4103/ijnmr.ijnmr_129_21. eCollection 2022 Sep-Oct.

DOI:10.4103/ijnmr.ijnmr_129_21
PMID:36524136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9745841/
Abstract

BACKGROUND

Due to the importance of psychological support for women during menopause as a period with a high prevalence of mental health problems, this study aimed to evaluate the effect of the essential oil of lavender-Bergamot (La-Ber) and Mindfulness-Based Intervention (MBI) on sexual function, anxiety (primary outcome), and depression score (secondary outcome) in postmenopausal women with sexual dysfunction.

MATERIALS AND METHODS

This controlled randomized trial with a factorial design was performed on 132 postmenopausal women. Participants were randomly allocated into four equal groups: Aromatherapy-Routine Care (Aroma-RC), MBI-Placebo (MBI-P), Aromatherapy-MBI (Aroma-MBI), or Routine Care-Placebo (RC-P). Two to three drops of La-Ber or a similar placebo were inhaled three times a day for 8 weeks. Eight sessions of MBI intervention were conducted. At the end of the intervention and eight weeks afterward, the outcomes were assessed.

RESULTS

The sexual function score improved significantly in Aroma-MBI (adjusted Mean Difference [aMD]: 2.4, 95% CI: 0.01 to 4.80) and MBI-P (aMD: 2.6, 95% CI: 0.2 to 5.1) groups compared to the RC-P group. The anxiety score was reduced in the Aroma-RC group at the end of the intervention (aMD: -4.12, 95% CI: -7.41 to -0.72; = 0.020) and eight weeks later as well as in the Aroma-MBI group. In terms of depression, the mean score of depression was significantly lower than the RC-P group in the Aroma-RC group at the end of the intervention ( = 0.011).

CONCLUSIONS

MBI and aromatherapy seem effective on sexual function and menopausal anxiety. MBI improves sexual function, while aromatherapy ameliorated anxiety and depression.

摘要

背景

由于更年期女性心理健康问题高发,心理支持对她们至关重要,本研究旨在评估薰衣草 - 佛手柑精油(La - Ber)和基于正念的干预(MBI)对性功能障碍的绝经后女性性功能、焦虑(主要结局)和抑郁评分(次要结局)的影响。

材料与方法

本采用析因设计的对照随机试验,对132名绝经后女性进行了研究。参与者被随机分为四组,每组人数相等:芳香疗法 - 常规护理组(Aroma - RC)、MBI - 安慰剂组(MBI - P)、芳香疗法 - MBI组(Aroma - MBI)或常规护理 - 安慰剂组(RC - P)。每天吸入两到三滴La - Ber或类似安慰剂,持续8周,每天3次。进行了8次MBI干预课程。在干预结束时及之后8周评估结局。

结果

与RC - P组相比,Aroma - MBI组(调整后平均差[aMD]:2.4,95%置信区间[CI]:0.01至4.80)和MBI - P组(aMD:2.6,95% CI:0.2至5.1)的性功能评分显著改善。干预结束时(aMD: - 4.12,95% CI: - 7.41至 - 0.72;P = 0.020)及8周后,Aroma - RC组的焦虑评分降低,Aroma - MBI组也降低。在抑郁方面,干预结束时Aroma - RC组的抑郁平均评分显著低于RC - P组(P = 0.011)。

结论

MBI和芳香疗法似乎对性功能和更年期焦虑有效。MBI改善性功能,而芳香疗法改善焦虑和抑郁。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ffd/9745841/b0dc108b7d3f/IJNMR-27-392-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ffd/9745841/b0dc108b7d3f/IJNMR-27-392-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ffd/9745841/b0dc108b7d3f/IJNMR-27-392-g001.jpg

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