Research Center for Evidence-Based Medicine, Iranian EBM Centre, A Joanna Briggs Institute Affiliated Group, Tabriz University of Medical Sciences, Tabriz, Iran.
Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Complement Ther Clin Pract. 2020 May;39:101150. doi: 10.1016/j.ctcp.2020.101150. Epub 2020 Mar 20.
The objective of this review was to evaluate systematically the effectiveness of Lavender aromatherapy on physical and psychological symptoms in menopausal women.
A comprehensive systematic literature search in the electronic databases including the Cochrane Library, MEDLINE (PubMed), Ovid, Embase, Scopus, ProQuest, Web of science, and Google scholar, as well as Magiran, SID, and Irandoc for Persian literature review up to January 2020. All Randomized controlled trials, and quasi-experimental studies that evaluated the impact of aromatherapy with lavender alone or in combination with other aromas on physical and psychological symptoms in menopausal women were included in this systematic review.
Sixteen interventional studies consisted of 1092 postmenopausal women included in systematic review. Eight of eligible studies with 493 participants included in meta-analysis. There were significant between group differences in menopausal symptoms (standardized mean difference (SMD) = -1.39, 95% confidence interval (CI): 1.98 to -0.80, I = 76%; four trials, 236 participants); sleep quality score (SMD = -2.16, 95%CI: -3.77 to -0.54, I = 95%; three studies, 199 participants); systolic blood pressure (MD = -5.34 mmHg, 95% CI: -7.40 to -3.29, I = 10%; two study, 114 participants); diastolic blood (MD = -5.06 mmHg, 95% CI: -7.55 to -2.57, I = 0%; two study, 114 participants). Aromatherapy had positive effect on sexual function, self-esteem, anxiety, hot flash, but it had negative impact on triglyceride and high density lipoprotein compared to placebo (p < 0.05).
Aromatherapy with Lavender in postmenopausal women may cause an improvement in most of physical and psychological symptoms. Further high quality studies especially with focus on the adverse events are suggested globally.
本综述的目的是系统评估薰衣草芳香疗法对更年期妇女身体和心理症状的疗效。
我们对包括 Cochrane 图书馆、MEDLINE(PubMed)、Ovid、Embase、Scopus、ProQuest、Web of science 和 Google Scholar 在内的电子数据库以及 Magiran、SID 和 Irandoc 进行了全面的系统文献检索,以对波斯语文献进行综述,检索时间截至 2020 年 1 月。本系统综述纳入了单独使用薰衣草或与其他香气混合使用的芳香疗法对更年期妇女身体和心理症状影响的所有随机对照试验和准实验研究。
共有 16 项干预性研究纳入了本系统综述,共纳入 1092 名绝经后妇女。其中有 8 项符合条件的研究共纳入 493 名参与者进行了荟萃分析。在更年期症状(标准化均数差(SMD)=-1.39,95%置信区间(CI):1.98 至 -0.80,I²=76%;四项试验,236 名参与者)、睡眠质量评分(SMD=-2.16,95%CI:-3.77 至 -0.54,I²=95%;三项研究,199 名参与者)、收缩压(MD=-5.34mmHg,95%CI:-7.40 至 -3.29,I²=10%;两项研究,114 名参与者)和舒张压(MD=-5.06mmHg,95%CI:-7.55 至 -2.57,I²=0%;两项研究,114 名参与者)方面,组间差异有统计学意义。与安慰剂相比,芳香疗法对性功能、自尊、焦虑、热潮红有积极影响,但对甘油三酯和高密度脂蛋白有负面影响(p<0.05)。
薰衣草芳香疗法可改善更年期妇女的大部分身体和心理症状。建议全球开展更多高质量的研究,特别是关注不良反应的研究。