Faculty of Medicine and Health, School of Health Science, The University of Sydney, Sydney, New South Wales, Australia.
School of Medicine, Medical Sciences and Nutrition, The University of Aberdeen, Aberdeen, UK.
Obes Rev. 2023 Mar;24(3):e13537. doi: 10.1111/obr.13537. Epub 2022 Dec 18.
Consuming a greater proportion of total energy intake earlier in the day rather than in the evening is proposed to positively influence weight loss and health, potentially due to greater synchronization of human body circadian rhythms. This systematic review provides an update on existing evidence regarding earlier distributed eating patterns in weight loss interventions. Using a robust search strategy in five electronic databases, nine randomized controlled trials investigating the impact of energy intake distribution on weight loss were identified. Following critical appraisal, a random-effects meta-analyses found that, in the context of an energy-reduced diet, distributing energy intake with a focus on earlier intake resulted in significantly greater weight loss (-1.23 kg; 95% CI 2.40, -0.06, p = 0.04). Improvements in HOMA-IR, fasting glucose, and LDL cholesterol were also seen. The current study provides a timely update on the evidence linking distribution of total daily energy intake and health, showing that a focus on earlier intakes can result in greater short-term weight loss compared with later intakes. Future studies are needed to elucidate the impact that earlier intakes may have on weight management and metabolic health.
相较于晚上，一天中早些时候摄入更多的总能量被认为可以积极影响体重减轻和健康，这可能是由于人体昼夜节律同步性更好。本系统综述更新了关于减肥干预中较早分配进食模式的现有证据。我们使用五个电子数据库中的强大搜索策略，确定了九项随机对照试验，以调查能量摄入分布对体重减轻的影响。经过严格评价，随机效应荟萃分析发现，在能量减少饮食的背景下，重点关注较早摄入的能量摄入分布会导致体重显著减轻（-1.23kg；95%CI 2.40，-0.06，p=0.04）。还观察到 HOMA-IR、空腹血糖和 LDL 胆固醇的改善。本研究及时更新了与总日能量摄入和健康分布相关的证据，表明与较晚摄入相比，更关注较早摄入可以带来更大的短期体重减轻。需要进一步的研究来阐明较早摄入对体重管理和代谢健康的影响。
