Clavijo-Moran Hugo Juan Camilo, Álvarez-García Daniela, Pinilla-Monsalve Gabriel D, Muñoz-Ospina Beatriz, Orozco Jorge
Centro de Investigaciones Clínicas, Fundación Valle del Lili, Cali, Colombia.
Departamento de Neurocirugía, Fundación Valle del Lili, Cali, Colombia.
Front Psychol. 2022 Dec 1;13:1018176. doi: 10.3389/fpsyg.2022.1018176. eCollection 2022.
Cognitive impairment is frequent among people living with Parkinson's disease: up to 40% of patients exhibit symptoms of mild cognitive impairment and 25% meet the criteria for dementia. Parkinson's Disease Cognitive Rating Scale (PD-CRS) is one of the recommended scales by the Movement Disorders Society Task Force for level 1 screening of dementia. However, its psychometric properties have not been studied in the Colombian population.
A cross-sectional study was conducted on 100 patients with Parkinson's disease diagnosed by a movement disorders neurologist. Patients were evaluated with PD-CRS and MoCA. Principal component analysis was conducted, and then confirmatory factor analysis was implemented through the maximum-likelihood method. Internal consistency was evaluated using Cronbach . Convergent and divergent validity were also calculated and concurrent validity with the MoCA was assessed.
62% were males. Their median age was 68 years (IQR 57-74) and the median disease duration was 4 years (IQR 2-9). 77% were classified in early stages (Hoehn and Yahr stage ≤ 2), while the MDS-UPDRS part III score was 25 (IQR 15.5-38). In the principal component factor analysis, the pattern matrix unveiled a mnesic and a non-mnesic domain. Confirmatory factor analysis showed similar explanatory capacity ( ≥ 0.50) for items other than naming ( = 0.34). Cronbach's for the full 9-items instrument was 0.74. MoCA and PD-CRS total scores were correlated ( = 0.71, = 0.000). Assuming a cut-off score of 62 points, there is an agreement of 89% with the definition of dementia by MoCA for Colombia ( = 0.59; = 0.000).
PD-CRS has acceptable psychometric properties for the Colombian population and has significant correlation and agreement with a validated scale (MoCA).
认知障碍在帕金森病患者中很常见：高达40%的患者表现出轻度认知障碍症状，25%符合痴呆症标准。帕金森病认知评定量表（PD-CRS）是运动障碍协会特别工作组推荐的用于痴呆症一级筛查的量表之一。然而，其心理测量特性尚未在哥伦比亚人群中进行研究。
对100名由运动障碍神经科医生诊断为帕金森病的患者进行了一项横断面研究。患者接受了PD-CRS和蒙特利尔认知评估量表（MoCA）评估。进行了主成分分析，然后通过最大似然法实施验证性因子分析。使用克朗巴哈系数评估内部一致性。还计算了聚合效度和区分效度，并评估了与MoCA的同时效度。
62%为男性。他们的年龄中位数为68岁（四分位间距57 - 74），疾病持续时间中位数为4年（四分位间距2 - 9）。77%被归类为早期阶段（霍恩和雅尔分期≤2期），而运动障碍协会统一帕金森病评定量表（MDS-UPDRS）第三部分得分是25分（四分位间距15.5 - 38）。在主成分因子分析中，模式矩阵揭示了一个记忆领域和一个非记忆领域。验证性因子分析显示，除命名项目外（载荷 = 0.34），其他项目具有相似的解释能力（≥0.50）。9项完整量表的克朗巴哈系数为0.74。MoCA和PD-CRS总分具有相关性（r = 0.71，p = 0.000）。假设临界值为62分，与哥伦比亚MoCA对痴呆症的定义一致性为89%（κ = 0.59；p = 0.000）。
PD-CRS对于哥伦比亚人群具有可接受的心理测量特性，并且与一个经过验证的量表（MoCA）具有显著的相关性和一致性。
