Rosca Elena Cecilia, Simu Mihaela
Department of Neurology, Victor Babes University of Medicine and Pharmacy Timisoara, Eftimie Murgu Sq. No. 2, 300041 Timișoara, Romania.
Department of Neurology, Clinical Emergency County Hospital Timisoara, Bd. Iosif Bulbuca No. 10, 300736 Timisoara, Romania.
Brain Sci. 2020 Aug 25;10(9):588. doi: 10.3390/brainsci10090588.
The aim of the present systematic review was to examine the evidence on the accuracy and psychometric properties of the Parkinson's Disease-Cognitive Rating Scale (PD-CRS) for evaluating the presence of cognitive impairment in patients with Parkinson's disease (PD) as well as to highlight the quality and quantity of research available on the use of the PD-CRS in this population. We searched four databases from inception until July 2020. Eight studies, published between 2008 and 2020, met the inclusion criteria: One cross-sectional study in which participants were assessed with the index test (PD-CRS) and a reference standard diagnostic assessment, in accordance with the Level II criteria of the International Parkinson and Movement Disorder Society (MDS); one case-control study comparing the PD-CRS to an extensive battery of tests (i.e., MDS Level II diagnosis); and six studies comparing the PD-CRS to other short cognitive batteries. In patients with Parkinson's disease, the PD-CRS test provides information about cortical and sub-cortical cognitive functions. Even if it demonstrated good psychometric properties, the results regarding the optimal threshold for detecting mild cognitive impairment and dementia in PD are somewhat inconsistent. Further cross-sectional studies are necessary to examine the optimum cut-off score for detecting cognitive dysfunction in PD patients.
本系统评价的目的是审查帕金森病认知评定量表（PD-CRS）在评估帕金森病（PD）患者认知障碍存在方面的准确性和心理测量特性的证据，并突出关于该人群使用PD-CRS的现有研究的质量和数量。我们检索了四个数据库，从创建至2020年7月。2008年至2020年间发表的八项研究符合纳入标准：一项横断面研究，根据国际帕金森和运动障碍协会（MDS）的二级标准，参与者接受了指标测试（PD-CRS）和参考标准诊断评估；一项病例对照研究，将PD-CRS与一系列广泛的测试（即MDS二级诊断）进行比较；以及六项将PD-CRS与其他简短认知测试组进行比较的研究。在帕金森病患者中，PD-CRS测试提供了有关皮质和皮质下认知功能的信息。即使它表现出良好的心理测量特性，但关于检测PD患者轻度认知障碍和痴呆的最佳阈值的结果仍有些不一致。需要进一步的横断面研究来检查检测PD患者认知功能障碍的最佳临界值。
