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甲状腺滤泡细胞型肿瘤伴可疑甲状腺癌细胞的细胞学诊断:一家地区综合医院的回顾性研究。

Thyroid carcinoma in nodules with Thy3 cytology: Retrospective study in a district general hospital.

机构信息

Royal Lancaster Infirmary.

出版信息

Acta Biomed. 2022 Dec 16;93(6):e2022288. doi: 10.23750/abm.v93i6.13528.

Abstract

Background and Aim Thyroid cancer is the most common malignant endocrine tumour. Fine needle aspiration cytology plays an important role in diagnosis of these tumours. The aim of the current study was to determine thyroid cancer risk for Thy3 cytology over a seven-year period from 2015 to 2021 at Royal Lancaster Infirmary, UK. Methods 206 medical records with Thy3 cytology were retrospectively reviewed from January 2015 to December 2021. Patients were classified into two groups: Thy3a and Thy3f. Histopathology reports were compared with cytology reports in order to determine malignancy rates. Results 18.9% of male patients and 23% of female patients had a malignant histology The average overall malignancy rate was 22.2%. More specifically, 22% of Thy3a and 22.4% of Thy3f were malignant. 22 patients eventually underwent completion thyroidectomy of which 6 patients had malignancy in the contralateral lobe. Conclusion Malignancy rates at our center was lower as compared to the national data rates.

摘要

背景与目的

甲状腺癌是最常见的恶性内分泌肿瘤。细针穿刺细胞学检查在这些肿瘤的诊断中起着重要作用。本研究的目的是确定 2015 年至 2021 年期间英国皇家兰开夏郡医院(Royal Lancaster Infirmary)Thy3 细胞学 7 年内的甲状腺癌风险。

方法

对 2015 年 1 月至 2021 年 12 月的 206 份 Thy3 细胞学的病历进行回顾性分析。患者分为 Thy3a 和 Thy3f 两组。将组织病理学报告与细胞学报告进行比较,以确定恶性肿瘤的发生率。

结果

18.9%的男性患者和 23%的女性患者存在恶性组织学。总的恶性肿瘤发生率平均为 22.2%。具体而言,Thy3a 组的 22%和 Thy3f 组的 22.4%为恶性肿瘤。22 名患者最终接受了全甲状腺切除术,其中 6 名患者对侧叶有恶性肿瘤。

结论

与全国数据相比,本中心的恶性肿瘤发生率较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7d6/9828909/59ed178e1b1f/ACTA-93-288-g001.jpg

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