Kreiner C F
Adatomed GmbH, München, FRG.
Dev Ophthalmol. 1987;14:11-9. doi: 10.1159/000414359.
In conclusion, one can state that silicones are one of the most inert materials available for use in medical field today. They meet all the requirements for implants, summarized in table V, and can be considered as the ideal material for intraocular use, provided that the polymer is absolutely pure and free of any kind of residues. For silicone rubbers the following specifications have to be fulfilled: the material has to be free of reactive prepolymers and of catalyzers, the filler should be of the same chemical nature as the basic material and should be chemically bound to the backbone of the polymer, to avoid any kind of migration out of the polymer. For silicone oils, the following criteria are desirable: the oil has to be practically free of low molecular components, mainly cyclohexanes, the molecular weight distribution should be as small as possible and the oil should be free of catalysts.
总之，可以说硅酮是当今医学领域可用的最惰性材料之一。它们满足表V中总结的植入物的所有要求，并且只要聚合物绝对纯净且不含任何残留物，就可被视为眼内使用的理想材料。对于硅橡胶，必须满足以下规格：材料必须不含反应性预聚物和催化剂，填料应与基础材料具有相同的化学性质，并应与聚合物主链化学键合，以避免任何种类的物质从聚合物中迁移出来。对于硅油，理想的标准如下：油必须几乎不含低分子成分，主要是环己烷，分子量分布应尽可能小，并且油应不含催化剂。
