Stolba U, Binder S, Velikay M, Wedrich A
University of Vienna, Department of Ophthalmology B, Austria.
Graefes Arch Clin Exp Ophthalmol. 1996 Jan;234(1):55-7. doi: 10.1007/BF00186519.
To evaluate a potential effect of silicone oil on flexible silicone intraocular lenses, four lenses (STAAR AA-4203) were stored in silicone oil under sterile conditions for periods between 1 month and 3 years.
The edge and surface of the lenses were examined by scanning electron micrography and the findings compared with a lens of the same model which had been stored in Ringer's solution for 2 years.
After 1 year of silicone oil exposure, droplets of different sizes adherent to the surface of the lens were found. These changes proceeded to a wave-like appearance of the surface after 2 and 3 years of storage, so that a continuous layer of silicone oil polymers is probably covering the intraocular lens.
Optical interference has to be considered a possibility if it turns out that the droplets cannot be removed during silicone oil evacuation. Consequently silicone intraocular lenses without hydrophilic preparation of the surface should not be implanted in eyes undergoing combined anterior and posterior segment surgery with silicone oil tamponade or in eyes with high risk for vitreoretinal complications.
为评估硅油对软性硅酮人工晶状体的潜在影响,将四片人工晶状体(STAAR AA - 4203)在无菌条件下于硅油中储存1个月至3年不等。
通过扫描电子显微镜检查人工晶状体的边缘和表面,并将结果与在林格氏液中储存2年的同型号人工晶状体进行比较。
硅油暴露1年后,发现镜片表面附着有不同大小的液滴。储存2年和3年后,这些变化发展为表面呈波浪状,以至于硅油聚合物的连续层可能覆盖了人工晶状体。
如果在硅油清除过程中发现液滴无法去除,则必须考虑光学干扰的可能性。因此,未经表面亲水性处理的硅酮人工晶状体不应植入接受硅油填充的眼前段和后段联合手术的眼睛或有玻璃体视网膜并发症高风险的眼睛中。