Department of Economics and Finance, Jon M. Huntsman School of Business, Utah State University, Logan, Utah, United States of America.
PLoS One. 2022 Dec 20;17(12):e0278875. doi: 10.1371/journal.pone.0278875. eCollection 2022.
While prior research shows that pharmaceutical innovation generates measurable benefits for society, over the last 70 years, the innovative activities of pharmaceutical firms have dramatically declined. In this study, we develop and test the hypothesis that to innovate, pharmaceutical firms must have access to capital through well-developed financial markets. Using a broad cross-country sample from 1989 to 2016, we document that financial market development is associated with greater levels of pharmaceutical innovation. To draw stronger causal inferences, and to overcome potential endogeneity issues, we use both instrumental variable and difference-in-difference analysis. Our results suggest that access to capital markets plays a vital role in pharmaceutical innovation.
虽然先前的研究表明,药品创新为社会带来了可衡量的效益,但在过去的 70 年里,制药公司的创新活动却大幅减少。在这项研究中,我们提出并检验了一个假设,即制药公司若要进行创新,就必须通过发达的金融市场获得资金。我们利用 1989 年至 2016 年广泛的跨国样本,证明了金融市场发展与更高水平的药品创新之间存在关联。为了得出更有力的因果推断,并克服潜在的内生性问题,我们同时使用了工具变量法和双重差分法。研究结果表明,获得资本市场的渠道对于药品创新至关重要。