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基于卷积神经网络和双向长短期记忆的带权重损失的稳健多心跳分类。

A robust multiple heartbeats classification with weight-based loss based on convolutional neural network and bidirectional long short-term memory.

作者信息

Yang Mengting, Liu Weichao, Zhang Henggui

机构信息

Key Laboratory of Medical Electrophysiology, Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, (Collaborative Innovation Center for Prevention of Cardiovascular Diseases), Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China.

School of Medical Information and Engineering, Southwest Medical University, Luzhou, China.

出版信息

Front Physiol. 2022 Dec 5;13:982537. doi: 10.3389/fphys.2022.982537. eCollection 2022.

Abstract

Analysis of electrocardiogram (ECG) provides a straightforward and non-invasive approach for cardiologists to diagnose and classify the nature and severity of variant cardiac diseases including cardiac arrhythmia. However, the interpretation and analysis of ECG are highly working-load demanding, and the subjective may lead to false diagnoses and heartbeats classification. In recent years, many deep learning works showed an excellent role in accurate heartbeats classification. However, the imbalance of heartbeat classes is universal in most of the available ECG databases since abnormal heartbeats are always relatively rare in real life scenarios. In addition, many existing approaches achieved prominent results by removing noise and extracting features in data preprocessing, which relies heavily on powerful computers. It is a pressing need to develop efficient and automatic light weighted algorithms for accurate heartbeats classification that can be used in portable ECG sensors. This study aims at developing a robust and efficient deep learning method, which can be embedded into wearable or portable ECG monitors for classifying heartbeats. We proposed a novel and light weighted deep learning architecture with weight-based loss based on a convolutional neural network (CNN) and bidirectional long short-term memory (Bi-LSTM) that can automatically identify five types of ECG heartbeats according to the AAMI EC57 standard. It was also true that the raw ECG signals were simply segmented without noise removal and other feature extraction processing. Moreover, to tackle the challenge of classification bias due to imbalanced ECG datasets for different types of arrhythmias, we introduced a weight-based loss function to reduce the influence of over-weighted categories in the ECG dataset. For avoiding the influence of the division of validation dataset, k-fold method was adopted to improve the reliability of the model. The proposed algorithm is trained and tested on MIT-BIH Arrhythmia Database, and achieves an average of 99.33% accuracy, 93.67% sensitivity, 99.18% specificity, 89.85% positive prediction, and 91.65% F score.

摘要

心电图(ECG)分析为心脏病专家诊断和分类包括心律失常在内的各种心脏疾病的性质和严重程度提供了一种直接且非侵入性的方法。然而,心电图的解读和分析工作负荷极大,主观性可能导致误诊和心跳分类错误。近年来,许多深度学习研究在准确的心跳分类方面发挥了出色作用。然而,由于现实生活中心跳异常情况相对较少,大多数可用的心电图数据库中都存在心跳类别不平衡的问题。此外,许多现有方法通过在数据预处理中去除噪声和提取特征取得了显著成果,但这严重依赖强大的计算机。迫切需要开发高效、自动且轻量级的算法,用于在便携式心电图传感器中进行准确的心跳分类。本研究旨在开发一种强大且高效的深度学习方法,该方法可嵌入可穿戴或便携式心电图监测器中用于心跳分类。我们基于卷积神经网络(CNN)和双向长短期记忆网络(Bi-LSTM)提出了一种新颖的轻量级深度学习架构,该架构基于权重损失,能够根据AAMI EC57标准自动识别五种类型的心电图心跳。此外,原始心电图信号仅进行简单分割,无需去除噪声和其他特征提取处理。而且,为应对不同类型心律失常的心电图数据集不平衡导致的分类偏差挑战,我们引入了基于权重的损失函数,以减少心电图数据集中过度加权类别的影响。为避免验证数据集划分的影响,采用k折方法提高模型的可靠性。所提出的算法在MIT-BIH心律失常数据库上进行训练和测试,平均准确率达到99.33%,灵敏度为93.67%,特异性为99.18%,阳性预测率为89.85%,F值为91.65%。

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