Castellazzi Massimo Luca, Agostoni Carlo Virginio, Palella Jessica, Civeriati Daniela, Marchisio Paola, Nebbia Gabriella
Pediatric Emergency Department, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Pediatric Intermediate Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Front Pediatr. 2022 Dec 5;10:1051887. doi: 10.3389/fped.2022.1051887. eCollection 2022.
Ceftriaxone, a third-generation cephalosporin, is commonly used in pediatric patients and is generally well tolerated. Its more frequent adverse effects are biliary pseudolithiasis, urolithiasis, and hemolytic anemia. On the other hand, ceftriaxone-induced acute cholestatic hepatitis is a very rare condition, especially in children. Here, we describe a case of this condition in a young male child to highlight the importance of suspecting this drug-induced liver injury to achieve a prompt diagnosis.
头孢曲松，一种第三代头孢菌素，常用于儿科患者，且一般耐受性良好。其较常见的不良反应有胆汁假性结石、尿路结石和溶血性贫血。另一方面，头孢曲松所致急性胆汁淤积性肝炎是一种非常罕见的病症，尤其是在儿童中。在此，我们描述一名幼龄男童患此病的病例，以强调怀疑这种药物性肝损伤以实现快速诊断的重要性。
