Sagie A, Rotenberg Z, Weinberger I, Fuchs J, Agmon J
Massada Center for Heart Diseases, Beilinson Medical Center, Petah Tikva, Israel.
J Am Geriatr Soc. 1987 Oct;35(10):915-9. doi: 10.1111/j.1532-5415.1987.tb02291.x.
The hospital records of 126 patients over 75 years of age with transmural myocardial infarction initially treated in the coronary care unit were compared with a concurrent similar group of 94 patients admitted directly to the general medical wards. The in-hospital mortality rate for both groups together was 40%. The mortality rate within the coronary care unit was 24% as compared with 46% in the ward group (P less than 0.005). However, the mortality rate for the coronary care unit group as a whole (including those patients later transferred to the general ward) was 35 versus 46% in the ward group. Congestive heart failure and cardiogenic shock were the most frequent complications in both groups (47 and 30%, respectively), and they were the main cause of death. Patients with these complications were less likely to be successfully resuscitated, even in the coronary care unit. The overall incidence of serious ventricular arrhythmias and complete heart block was similar to that reported for younger patients. Eleven patients in the coronary care unit group were successfully resuscitated from these arrhythmias and eight survived to be discharged from hospital. In contrast, only two patients in the ward group were successfully resuscitated and eight (9%) patients died suddenly and the fatal event could not be diagnosed. We concluded that elderly patients with an acute myocardial infarction can benefit from early admission to a coronary care unit.
对126例75岁以上经冠状动脉监护病房(CCU)初始治疗的透壁性心肌梗死患者的医院记录,与同期直接收入普通内科病房的94例类似患者进行了比较。两组患者的院内死亡率合计为40%。冠状动脉监护病房内的死亡率为24%,而病房组为46%(P<0.005)。然而,冠状动脉监护病房组总体(包括后来转至普通病房的患者)的死亡率为35%,而病房组为46%。充血性心力衰竭和心源性休克是两组中最常见的并发症(分别为47%和30%),且是主要死因。即使在冠状动脉监护病房,有这些并发症的患者成功复苏的可能性也较小。严重室性心律失常和完全性心脏传导阻滞的总体发生率与年轻患者的报道相似。冠状动脉监护病房组中有11例患者从这些心律失常中成功复苏,8例存活出院。相比之下,病房组中只有2例患者成功复苏,8例(9%)患者突然死亡,且无法确诊致死事件。我们得出结论,急性心肌梗死老年患者早期入住冠状动脉监护病房可获益。