Kajikawa Keita, Nagoshi Narihito, Tsuji Osahiko, Suzuki Satoshi, Ozaki Masahiro, Takahashi Yohei, Yagi Mitsuru, Matsumoto Morio, Nakamura Masaya, Watanabe Kota
Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo 160-8582, Japan.
Diagnostics (Basel). 2022 Nov 28;12(12):2969. doi: 10.3390/diagnostics12122969.
The features of non-neoplastic lesions are often similar to those of intramedullary tumors, and a differential diagnosis is challenging to obtain in some cases. A surgical biopsy, which is performed on highly invasive tumors, should be avoided in cases of non-neoplastic lesions. Therefore, an accurate diagnosis is important prior to treatment. We evaluated 43 patients suspected of having spinal cord tumors and, finally, were diagnosed with non-neoplastic intramedullary lesions via magnetic resonance imaging. The patients commonly presented with myelitis. The patients with non-neoplastic neurological diseases had a significantly shorter symptom duration than those with intramedullary astrocytomas. The proportion of patients with non-neoplastic neurological diseases who presented with lesions at the cervical spinal level and focal lesions on axial imaging but without a spinal cord enlargement was significantly higher than that of patients with intramedullary astrocytomas. The current study aimed to distinguish spinal cord tumors from non-neoplastic intramedullary lesions based on their distinct features.
非肿瘤性病变的特征通常与髓内肿瘤相似，在某些情况下难以进行鉴别诊断。对于高度侵袭性肿瘤进行的手术活检，在非肿瘤性病变的情况下应避免。因此，在治疗前进行准确诊断很重要。我们评估了43例疑似脊髓肿瘤的患者，最终通过磁共振成像诊断为非肿瘤性髓内病变。这些患者通常表现为脊髓炎。非肿瘤性神经疾病患者的症状持续时间明显短于髓内星形细胞瘤患者。非肿瘤性神经疾病患者中，在颈椎水平出现病变且在轴向成像上有局灶性病变但无脊髓增粗的比例明显高于髓内星形细胞瘤患者。本研究旨在根据脊髓肿瘤和非肿瘤性髓内病变的不同特征进行区分。
