Department of Orthopaedics and Traumatology, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China ; The Laboratory and Clinical Research Institute for Pain, The University of Hong Kong, Pokfulam, Hong Kong, SAR, China.
Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois, United States.
Global Spine J. 2015 Oct;5(5):425-35. doi: 10.1055/s-0035-1549029. Epub 2015 Mar 31.
Study Design Broad narrative review. Objectives Intramedullary spinal cord tumors (IMSCT) are rare neoplasms that can potentially lead to severe neurologic deterioration, decreased function, poor quality of life, or death. As such, a better understanding of these lesions is needed. The following article, part one of a two-part series, addresses IMSCT with regards to their epidemiology, histology, pathophysiology, imaging characteristics, and clinical manifestations. Methods The authors performed an extensive review of the peer-reviewed literature addressing the aforementioned objectives. Results Numerous IMSCT exist with varying epidemiology. Each IMSCT has its own hallmark characteristics and may vary with regards to how aggressively they invade the spinal cord. These lesions are often difficult to detect and are often misdiagnosed. Furthermore, radiographically and clinically, these lesions may be difficult to distinguish from one another. Conclusions Awareness and understanding of IMSCT is imperative to facilitate an early diagnosis and plan management.
广泛的叙述性综述。目的：髓内脊髓肿瘤（IMSCT）是罕见的肿瘤，可能导致严重的神经恶化、功能下降、生活质量差或死亡。因此，需要更好地了解这些病变。本文是两部分系列的第一部分，针对 IMSCT 的流行病学、组织学、病理生理学、影像学特征和临床表现进行了讨论。方法：作者对上述目标进行了广泛的同行评审文献综述。结果：存在多种具有不同流行病学特征的 IMSCT。每种 IMSCT 都有其自身的特征，并且可能因其对脊髓的侵袭程度而有所不同。这些病变通常难以检测，并且经常被误诊。此外，这些病变在影像学和临床上可能难以与其他病变区分开来。结论：了解和认识 IMSCT 对于促进早期诊断和制定治疗计划至关重要。
