Luca Alina-Costina, Curpan Alexandrina-Stefania, Braha Elena Emanuela, Ţarcă Elena, Iordache Alin-Constantin, Luca Florin-Alexandru, Adumitrachioaiei Heidrun
Department of Mother and Child Medicine-Pediatric Cardiology, Faculty of Medicine, Gr. T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.
Sfânta Maria' Emergency Children's Hospital, 700309 Iasi, Romania.
Healthcare (Basel). 2022 Dec 5;10(12):2452. doi: 10.3390/healthcare10122452.
Childhood obesity has become a global public health issue and its assessment is essential, as an obese child is a future overweight or obese adult. Obesity is no longer a matter of exercising more and eating less, with several factors coming into play and dictating the pattern of fat accumulation and the ease/difficulty of reducing it. In the current paper, we aimed to analyze the cardiovascular impact of obesity in a large number of patients alongside the paraclinical changes that occur due to weight gain, and to perform an analysis on the increase in prevalence throughout our research. The main cardiovascular conditions identified were hypertension (15.36%), septal or concentric hypertrophic cardiomyopathy (11.15%), atherosclerosis risk (13.04%), and hypercholesterolemia (20.94%). We have used echocardiography to measure the thickness of epicardial adipose tissue (useful for assessing the patient's cardiovascular risk), and we observed that it was greater in children with moderate and severe obesity alongside diastolic dysfunction of the left ventricle in the whole group, without any connection with hypertension or coronary impairment. Obese children will be affected by increased cardiovascular mortality and morbidity in adulthood and they may experience early cardiovascular dysfunction. We want to strongly underline the importance and necessity of programs for the early detection and prevention of obesity and its complications, especially since interesting phenomena such as the "obesity paradox" exist and prove that obesity is far less understood than it is at a first glance.
儿童肥胖已成为一个全球公共卫生问题,对其进行评估至关重要,因为肥胖儿童未来很可能成为超重或肥胖的成年人。肥胖不再仅仅是多运动、少吃的问题,而是有多种因素在起作用,决定着脂肪堆积的模式以及减肥的难易程度。在本文中,我们旨在分析大量患者中肥胖对心血管的影响以及体重增加所导致的临床旁变化,并对我们研究期间患病率的上升情况进行分析。所确定的主要心血管病症包括高血压(15.36%)、间隔或同心性肥厚型心肌病(11.15%)、动脉粥样硬化风险(13.04%)以及高胆固醇血症(20.94%)。我们使用超声心动图来测量心外膜脂肪组织的厚度(有助于评估患者的心血管风险),并且我们观察到,在中度和重度肥胖儿童中该厚度更大,同时在整个群体中存在左心室舒张功能障碍,且与高血压或冠状动脉损伤无关。肥胖儿童在成年后将受到心血管死亡率和发病率上升的影响,并且他们可能会出现早期心血管功能障碍。我们想着重强调早期发现和预防肥胖及其并发症项目的重要性和必要性,特别是因为存在诸如“肥胖悖论”这样有趣的现象,这证明肥胖远非乍看之下那么简单。