Chemistry Department, Moscow State University, 119991 Moscow, Russia.
N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Science, 119991 Moscow, Russia.
Int J Mol Sci. 2022 Dec 9;23(24):15649. doi: 10.3390/ijms232415649.
We report herein the synthesis and full characterizations of the first examples of gallium complexes based on "privileged" aminobisphenolate ligands which are easily available. These complexes turned out to be extremely active in the ring-opening polymerization of ε-caprolactone even at room temperature and highly active in the ROP of L-lactide. The combination of factors such as the easy availability of these compounds and the supposedly low toxicity, together with the extremely high activity in ROP, allows us to consider these compounds as suitable for use on an industrial scale for the synthesis of biodegradable polymers for biomedical applications.
我们在此报告了首例基于“受优待的”氨基双酚配体的镓配合物的合成及全性质表征，这些配体很容易获得。这些配合物在室温下对ε-己内酯的开环聚合具有极高的活性，且对 L-丙交酯的开环聚合也具有极高的活性。这些化合物易于获得、毒性可能较低，再加上在 ROP 中具有极高的活性，这些因素结合在一起，使得我们可以考虑将这些化合物用于工业规模合成用于生物医学应用的可生物降解聚合物。
