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mTOR 信号网络在细胞生物学和人类疾病中的作用。

mTOR Signaling Network in Cell Biology and Human Disease.

机构信息

Department of Internal Medicine, College of Medicine, University of Cincinnati, Cincinnati, OH 45267, USA.

Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Lung Center, School of Medicine, University of California Davis, Davis, CA 95616, USA.

出版信息

Int J Mol Sci. 2022 Dec 18;23(24):16142. doi: 10.3390/ijms232416142.

Abstract

The mechanistic target of rapamycin (mTOR) is a serine/threonine protein kinase that regulates multiple processes, including gene transcription, protein synthesis, ribosome biogenesis, autophagy, cell metabolism, and cell growth [...].

摘要

雷帕霉素靶蛋白(mTOR)是一种丝氨酸/苏氨酸蛋白激酶,调节多种过程,包括基因转录、蛋白质合成、核糖体生物发生、自噬、细胞代谢和细胞生长[...]。

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