1-氨基烷基膦酸的脱氨反应：反应中间体和选择性。
Deamination of 1-Aminoalkylphosphonic Acids: Reaction Intermediates and Selectivity.
机构信息
Department of Physical and Quantum Chemistry, Faculty of Chemistry, Wrocław University of Science and Technology, ul. Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.
出版信息
Molecules. 2022 Dec 13;27(24):8849. doi: 10.3390/molecules27248849.
Deamination of 1-aminoalkylphosphonic acids in the reaction with HNO (generated "in situ" from NaNO) yields a mixture of substitution products (1-hydroxyalkylphosphonic acids), elimination products (vinylphosphonic acid derivatives), rearrangement and substitution products (2-hydroxylkylphosphonic acids) as well as HPO. The variety of formed reaction products suggests that 1-phosphonoalkylium ions may be intermediates in such deamination reactions.
1-氨基烷基膦酸与 HNO 的反应（由 NaNO“原位”生成）生成取代产物（1-羟烷基膦酸）、消除产物（乙烯基膦酸衍生物）、重排和取代产物（2-羟烷基膦酸）以及 HPO 的混合物。形成的反应产物种类繁多，这表明 1-膦烷氧离子可能是此类脱氨反应的中间体。
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