Su Qinyue, Chen Yuwei, Chen Weiwei, Chen Ying, Chen Erzhen
Department of Emergency, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China. Corresponding author: Chen Erzhen, Email:
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2022 Nov;34(11):1222-1226. doi: 10.3760/cma.j.cn121430-20220711-00646.
Sepsis associated-acute kidney injury (SA-AKI) is a common complication of sepsis, which has a high incidence and is closely related to a poor prognosis. However, delayed diagnosis and non-specific treatments make it difficult to systematically manage SA-AKI. Based on massive clinical data, machine learning could build prediction models, which provide alarms and suggestions for the clinical decision support system. Although there are still many challenges such as poor interpretability, it has shown clinical application value in SA-SKI risk prediction, imaging diagnosis, subtype identification, prognosis assessment, and so on. Based on a brief introduction of machine learning, this article reviews the application, limitations, and future directions of machine learning in the diagnosis and treatment of SA-AKI, and explores the possibility of machine learning in the medical field, in order to promote the development of precision medicine and intelligent medicine.
脓毒症相关性急性肾损伤(SA-AKI)是脓毒症常见的并发症,发病率高且与预后不良密切相关。然而,诊断延迟和治疗缺乏特异性使得SA-AKI难以得到系统管理。基于大量临床数据,机器学习可构建预测模型,为临床决策支持系统提供警报和建议。尽管仍存在诸如可解释性差等诸多挑战,但它已在SA-AKI风险预测、影像诊断、亚型识别、预后评估等方面展现出临床应用价值。本文在简要介绍机器学习的基础上,综述机器学习在SA-AKI诊疗中的应用、局限性及未来方向,探讨机器学习在医学领域的应用前景,以推动精准医学和智能医学的发展。