Braunstein Eric D, Kagan Ruth D, Olshan David S, Gabriels James K, Thomas George, Ip James E, Markowitz Steven M, Lerman Bruce B, Liu Christopher F, Cheung Jim W
Division of Cardiology, Weill Cornell Medicine, NewYork-Presbyterian Hospital, New York, New York, USA.
J Cardiovasc Electrophysiol. 2023 Mar;34(3):710-717. doi: 10.1111/jce.15789. Epub 2022 Dec 30.
Left bundle branch area pacing (LBBP) has emerged as an alternative method for conduction system pacing. While initial experience with delivery systems for stylet-driven and lumenless lead implantation for LBBP has been described, data comparing outcomes of stylet-driven versus lumenless lead implantation for LBBP are limited. In this study, we compare success rates and outcomes of LBBP with stylet-driven versus lumenless lead delivery systems.
Eighty-three consecutive patients (mean age 74.1 ± 11.2 years; 56 [68%] male) undergoing attempted LBBP at a single institution were identified. Cases were grouped by lead delivery systems used: stylet-driven (n = 53) or lumenless (n = 30). Baseline characteristics and procedural findings were recorded and compared between the cohorts. Intermediate term follow-up data on ventricular lead parameters were also compared.
Baseline characteristics were similar between groups. Successful LBBP was achieved in 77% of patients, with similar success rates between groups (76% in stylet-driven, 80% in lumenless, p = 0.79), and rates of adjudicated LBB capture and other paced QRS parameters were also similar. Compared with the lumenless group, the stylet-driven group had significantly shorter procedure times (90 ± 4 vs. 112 ± 31 min, p = 0.004) and fluoroscopy times (10 ± 5 vs. 15 ± 6 min, p = 0.003). Ventricular lead parameters at follow-up were similar, and rates of procedural complications and need for lead revision were low in both groups.
Delivery systems for stylet-driven and for lumenless leads for LBBP have comparable acute success rates. Long-term follow-up of lead performance following use of the various delivery systems is warranted.
左束支区域起搏(LBBP)已成为传导系统起搏的一种替代方法。虽然已经描述了用于LBBP的探丝驱动和无腔导线植入输送系统的初步经验,但比较LBBP的探丝驱动与无腔导线植入结果的数据有限。在本研究中,我们比较了LBBP使用探丝驱动与无腔导线输送系统的成功率和结果。
确定了在单一机构接受LBBP尝试的83例连续患者(平均年龄74.1±11.2岁;56例[68%]为男性)。病例按使用的导线输送系统分组:探丝驱动组(n = 53)或无腔组(n = 30)。记录并比较队列之间的基线特征和手术结果。还比较了心室导线参数的中期随访数据。
两组之间的基线特征相似。77%的患者成功实现了LBBP,两组成功率相似(探丝驱动组为76%,无腔组为80%,p = 0.79),判定的LBB捕获率和其他起搏QRS参数也相似。与无腔组相比,探丝驱动组的手术时间明显更短(90±4 vs. 112±31分钟,p = 0.004),透视时间也更短(10±5 vs. 15±6分钟,p = 0.003)。随访时心室导线参数相似,两组的手术并发症发生率和导线修订需求率均较低。
LBBP的探丝驱动和无腔导线输送系统具有相当的急性成功率。有必要对使用各种输送系统后的导线性能进行长期随访。