Suppr超能文献

为异种移植研究辩护:因为动物福利问题,而不是不顾动物福利问题。

In defense of xenotransplantation research: Because of, not in spite of, animal welfare concerns.

机构信息

Department of Theology and Philosophy, Hendrickson Institute for Ethical Leadership, St. Mary's University of Minnesota, Winona, Minnesota, USA.

Operating Department Practice, Institute of Health and Social Care, School of Allied and Community Health, London South Bank University, London, UK.

出版信息

Xenotransplantation. 2023 Jan;30(1):e12791. doi: 10.1111/xen.12791. Epub 2022 Dec 27.

Abstract

It is envisioned that one day xenotransplantation will bring about a future where transplantable organs can be safely and efficiently grown in transgenic pigs to help meet the global organ shortage. While recent advances have brought this future closer, worries remain about whether it will be beneficial overall. The unique challenges and risks posed to humans that arise from transplanting across the species barrier, in addition to the costs borne by non-human animals, has led some to question the value of xenotransplantation altogether. In response, we defend the value of xenotransplantation research, because it can satisfy stringent welfare conditions on the permissibility of animal research and use. Along the way, we respond to the alleged concerns, and conclude that they do not currently warrant a cessation or a curtailing of xenotransplantation research.

摘要

人们设想,有朝一日异种移植将带来这样一个未来:可在转基因猪中安全有效地培育可移植器官,以帮助解决全球器官短缺问题。虽然最近的进展使这一未来更加接近,但人们仍然担心它是否总体上有益。由于跨越物种障碍进行移植给人类带来的独特挑战和风险,以及非人类动物所承受的成本,一些人完全质疑异种移植的价值。有鉴于此,我们捍卫异种移植研究的价值,因为它可以满足动物研究和使用的可允许性方面的严格福利条件。在此过程中,我们回应了所谓的担忧,并得出结论认为,目前这些担忧并不值得停止或限制异种移植研究。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验