Chang Munyoung, Ku Yunseo
Department of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University College of Medicine, 84 Heukseok-Ro, Dongjak-Gu, 06974, Seoul, South Korea.
Department of Electrical and Computer Engineering, Seoul National University, 1 Gwanak-Ro, Gwanak-Gu, 08826, Seoul, South Korea.
Environ Sci Pollut Res Int. 2023 Mar;30(13):37440-37448. doi: 10.1007/s11356-022-24956-9. Epub 2022 Dec 27.
Asthma is a common respiratory disease that is affected by air pollutants and meteorological factors. In this study, we developed models that predict the daily number of patients receiving treatment for asthma using air pollution and meteorological data. A neural network with long short-term memory (LSTM) and fully connected (FC) layers was used. The daily number of asthma patients in the city of Seoul, the capital of South Korea, was collected from the National Health Insurance Service. The data from 2015 to 2018 were used as the training and validation datasets for model development. Unseen data from 2019 were used for testing. The daily number of asthma patients per 100,000 inhabitants was predicted. The LSTM-FC neural network model achieved a Pearson correlation coefficient of 0.984 (P < 0.001) and root mean square error of 3.472 between the predicted and original values on the unseen testing dataset. The factors that impacted the prediction were the number of asthma patients in the previous time step before the predicted date, type of day (regular day and day after a holiday), minimum temperature, SO, daily changes in the amount of cloud, and daily changes in diurnal temperature range. We successfully developed a neural network that predicts the onset and exacerbation of asthma, and we identified the crucial influencing air pollutants and meteorological factors. This study will help us to establish appropriate measures according to the daily predicted number of asthma patients and reduce the daily onset and exacerbation of asthma in the susceptible population.
哮喘是一种常见的呼吸系统疾病,受空气污染物和气象因素影响。在本研究中,我们利用空气污染和气象数据开发了预测每日接受哮喘治疗患者数量的模型。使用了具有长短期记忆(LSTM)和全连接(FC)层的神经网络。韩国首都首尔市哮喘患者的每日数量数据来自国民健康保险服务。2015年至2018年的数据用作模型开发的训练和验证数据集。2019年的未见数据用于测试。预测了每10万居民中哮喘患者的每日数量。在未见测试数据集上,LSTM-FC神经网络模型在预测值与原始值之间的皮尔逊相关系数为0.984(P < 0.001),均方根误差为3.472。影响预测的因素包括预测日期前一个时间步的哮喘患者数量、日期类型(平日和节假日后一天)、最低温度、二氧化硫、云量的每日变化以及日温差的每日变化。我们成功开发了一个预测哮喘发作和加重的神经网络,并确定了关键的影响空气污染物和气象因素。本研究将帮助我们根据每日预测的哮喘患者数量制定适当措施,减少易感人群中哮喘的每日发作和加重。