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1
Reply: Intraamniotic infection/inflammation in threatened midtrimester miscarriage, cervical insufficiency, and preterm labor without cervical changes.回复：孕中期流产、宫颈机能不全以及无宫颈变化的早产威胁中的羊膜腔内感染/炎症。
Am J Obstet Gynecol. 2023 Apr;228(4):480-483. doi: 10.1016/j.ajog.2022.12.312. Epub 2022 Dec 24.
2
The role of intraamniotic inflammation in threatened midtrimester miscarriage.羊膜内炎症在中期妊娠流产先兆中的作用。
Am J Obstet Gynecol. 2022 Dec;227(6):895.e1-895.e13. doi: 10.1016/j.ajog.2022.07.007. Epub 2022 Jul 16.
3
Human β-defensin-1: A natural antimicrobial peptide present in amniotic fluid that is increased in spontaneous preterm labor with intra-amniotic infection.人β-防御素-1：一种存在于羊水中的天然抗菌肽，在伴有羊膜内感染的自发性早产中增加。
Am J Reprod Immunol. 2018 Oct;80(4):e13031. doi: 10.1111/aji.13031. Epub 2018 Aug 12.
4
The frequency and significance of intraamniotic inflammation in patients with cervical insufficiency.宫颈机能不全患者羊膜腔内炎症的发生率及意义。
Am J Obstet Gynecol. 2008 Jun;198(6):633.e1-8. doi: 10.1016/j.ajog.2007.11.047. Epub 2008 Mar 14.
5
Infection and labor. VIII. Microbial invasion of the amniotic cavity in patients with suspected cervical incompetence: prevalence and clinical significance.感染与分娩。八、疑似宫颈机能不全患者羊膜腔的微生物入侵：发生率及临床意义。
Am J Obstet Gynecol. 1992 Oct;167(4 Pt 1):1086-91. doi: 10.1016/s0002-9378(12)80043-3.
6
Human β-defensin-3 participates in intra-amniotic host defense in women with labor at term, spontaneous preterm labor and intact membranes, and preterm prelabor rupture of membranes.人β-防御素-3参与足月、自发性早产胎膜未破和早产胎膜早破孕妇羊水中的宫内宿主防御。
J Matern Fetal Neonatal Med. 2020 Dec;33(24):4117-4132. doi: 10.1080/14767058.2019.1597047. Epub 2019 Apr 18.
7
Evidence of perturbations of the cytokine network in preterm labor.早产中细胞因子网络紊乱的证据。
Am J Obstet Gynecol. 2015 Dec;213(6):836.e1-836.e18. doi: 10.1016/j.ajog.2015.07.037. Epub 2015 Jul 29.
8
Low amniotic fluid glucose levels are a specific but not a sensitive marker for subclinical intrauterine infections in patients in preterm labor with intact membranes.羊水葡萄糖水平低是胎膜完整的早产患者亚临床宫内感染的一个特异性而非敏感性标志物。
Am J Obstet Gynecol. 1994 Aug;171(2):365-70; discussion 370-1. doi: 10.1016/s0002-9378(94)70036-2.
9
Funisitis is more common in cervical insufficiency than in preterm labor and preterm premature rupture of membranes.脐带炎在宫颈机能不全中比在早产和胎膜早破中更常见。
J Perinat Med. 2016 Jul 1;44(5):523-9. doi: 10.1515/jpm-2015-0123.
10
Twenty-four percent of patients with clinical chorioamnionitis in preterm gestations have no evidence of either culture-proven intraamniotic infection or intraamniotic inflammation.早产临床绒毛膜羊膜炎患者中有24%没有经培养证实的羊膜腔内感染或羊膜腔内炎症的证据。
Am J Obstet Gynecol. 2017 Jun;216(6):604.e1-604.e11. doi: 10.1016/j.ajog.2017.02.035. Epub 2017 Feb 28.

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1
Prediction of late-onset preeclampsia using plasma proteomics: a longitudinal multi-cohort study.利用血浆蛋白质组学预测晚发型子痫前期：一项纵向多队列研究
Sci Rep. 2024 Dec 28;14(1):30813. doi: 10.1038/s41598-024-81277-2.
2
Postpartum antihypertensive treatment: Is there a correlation to placental lesions?产后降压治疗：与胎盘病变有关吗？
Arch Gynecol Obstet. 2024 Jul;310(1):453-459. doi: 10.1007/s00404-023-07263-7. Epub 2023 Oct 30.

本文引用的文献

1
The role of intraamniotic inflammation in threatened midtrimester miscarriage.羊膜内炎症在中期妊娠流产先兆中的作用。
Am J Obstet Gynecol. 2022 Dec;227(6):895.e1-895.e13. doi: 10.1016/j.ajog.2022.07.007. Epub 2022 Jul 16.
2
Evidence that antibiotic administration is effective in the treatment of a subset of patients with intra-amniotic infection/inflammation presenting with cervical insufficiency.有证据表明，对于部分因宫颈机能不全而出现羊膜腔内感染/炎症的患者，抗生素治疗是有效的。
Am J Obstet Gynecol. 2019 Aug;221(2):140.e1-140.e18. doi: 10.1016/j.ajog.2019.03.017. Epub 2019 Mar 28.
3
Patients with acute cervical insufficiency without intra-amniotic infection/inflammation treated with cerclage have a good prognosis.急性宫颈功能不全且无羊膜腔内感染/炎症的患者，经环扎术治疗后预后良好。
J Perinat Med. 2019 Jul 26;47(5):500-509. doi: 10.1515/jpm-2018-0388.
4
The frequency and clinical significance of intra-amniotic inflammation in women with preterm uterine contractility but without cervical change: do the diagnostic criteria for preterm labor need to be changed?子宫收缩但宫颈无变化的早产女性羊膜腔内炎症的频率及临床意义：早产的诊断标准是否需要改变？
J Matern Fetal Neonatal Med. 2012 Aug;25(8):1212-21. doi: 10.3109/14767058.2011.629256. Epub 2012 Apr 25.
5
The frequency and significance of intraamniotic inflammation in patients with cervical insufficiency.宫颈机能不全患者羊膜腔内炎症的发生率及意义。
Am J Obstet Gynecol. 2008 Jun;198(6):633.e1-8. doi: 10.1016/j.ajog.2007.11.047. Epub 2008 Mar 14.
6
Infection and labor. VIII. Microbial invasion of the amniotic cavity in patients with suspected cervical incompetence: prevalence and clinical significance.感染与分娩。八、疑似宫颈机能不全患者羊膜腔的微生物入侵：发生率及临床意义。
Am J Obstet Gynecol. 1992 Oct;167(4 Pt 1):1086-91. doi: 10.1016/s0002-9378(12)80043-3.

Reply: Intraamniotic infection/inflammation in threatened midtrimester miscarriage, cervical insufficiency, and preterm labor without cervical changes.

作者信息

Yoon Bo Hyun, Romero Roberto, Oh Kyung Joon, Kim Hyeon Ji, Jung Eunjung, Gotsch Francesca, Suksai Manaphat

机构信息

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea; Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.

Perinatology Research Branch, Division of Obstetrics and Maternal-Fetal Medicine Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, and Detroit, MI.

出版信息

Am J Obstet Gynecol. 2023 Apr;228(4):480-483. doi: 10.1016/j.ajog.2022.12.312. Epub 2022 Dec 24.

DOI:10.1016/j.ajog.2022.12.312
PMID:36574872
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10448742/
Abstract
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