用于检测大肠杆菌热稳定肠毒素的幼鼠试验中的瑞士小鼠和近交系小鼠。
Swiss and inbred mice in the infant mouse test for the assay of Escherichia coli thermostable enterotoxin.
作者信息
Pestana de Castro A F, Serafim M B, Rangel H A, Guerrant R L
出版信息
Infect Immun. 1978 Dec;22(3):972-4. doi: 10.1128/iai.22.3.972-974.1978.
Abstract
Swiss and inbred mice (C3H, ASn, B10A, and C57) were used to assay different thermostable enterotoxins prepared from Escherichia coli strains 3 (human), E57 (swine), B41 (cattle), and S13 (sheep). All strains of mice detected enterotoxins, but some reacted better to a given thermostable enterotoxin preparation than other inbred strains. Since the results obtained with Swiss mice were more consistent than with inbred mice, the former are apparently more suitable in the infant mouse test.
摘要
使用瑞士小鼠和近交系小鼠（C3H、ASn、B10A和C57）来检测从大肠杆菌菌株3（人源）、E57（猪源）、B41（牛源）和S13（羊源）制备的不同热稳定肠毒素。所有品系的小鼠都能检测到肠毒素，但某些品系对特定的热稳定肠毒素制剂的反应比其他近交系品系更好。由于用瑞士小鼠获得的结果比近交系小鼠更一致，因此前者显然更适合用于幼鼠试验。
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